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[Mostrar más]Transplant-related toxicity is a barrier that contributes to the under utilization for 
which of the following diseases? 
A. Non-Hodgkin lymphoma 
B. Acute myeloid leukemia 
C. Sickle cell disease 
D. Neuroblastoma - ANSWER-C. Sickle cell disease 
Despite the success of HSCT in sickle cell disease, ...
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Añadir al carritoTransplant-related toxicity is a barrier that contributes to the under utilization for 
which of the following diseases? 
A. Non-Hodgkin lymphoma 
B. Acute myeloid leukemia 
C. Sickle cell disease 
D. Neuroblastoma - ANSWER-C. Sickle cell disease 
Despite the success of HSCT in sickle cell disease, ...
The cluster of differentiation system is used to: 
a. classify cell surface proteins on leukocytes. 
b. identify different types of cytokines. 
c. crossmatch for blood product transfusion. 
d. measure immune function. - ANSWER-The cluster of differentiation system 
classifies cell surface proteins. ...
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Añadir al carritoThe cluster of differentiation system is used to: 
a. classify cell surface proteins on leukocytes. 
b. identify different types of cytokines. 
c. crossmatch for blood product transfusion. 
d. measure immune function. - ANSWER-The cluster of differentiation system 
classifies cell surface proteins. ...
Myeloid - ANSWER-erythrocyte, platelets, neutrophil, basophil, eosinophil, 
monoblast, macrophage, monocyte 
lymphoid - ANSWER-pre- B cell, pre-t cell, plasma cell, natural killer cell, t 
lymphocyte 
innate immunity - ANSWER-occurs naturally- phagocytes release inflammatory 
mediators 
acquired imm...
Vista previa 2 fuera de 5 páginas
Añadir al carritoMyeloid - ANSWER-erythrocyte, platelets, neutrophil, basophil, eosinophil, 
monoblast, macrophage, monocyte 
lymphoid - ANSWER-pre- B cell, pre-t cell, plasma cell, natural killer cell, t 
lymphocyte 
innate immunity - ANSWER-occurs naturally- phagocytes release inflammatory 
mediators 
acquired imm...
hematopoietic stem cells - ANSWER-RBCs, WBCs, platelets 
Red marrow produces - ANSWER-hematopoietic stem cells 
Yellow marrow produces - ANSWER-stromal stem cells 
stromal stem cells produce - ANSWER-fat, cartilage and bone 
Hematopoietic stem cells develop - ANSWER-prior to birth, produced in the l...
Vista previa 1 fuera de 4 páginas
Añadir al carritohematopoietic stem cells - ANSWER-RBCs, WBCs, platelets 
Red marrow produces - ANSWER-hematopoietic stem cells 
Yellow marrow produces - ANSWER-stromal stem cells 
stromal stem cells produce - ANSWER-fat, cartilage and bone 
Hematopoietic stem cells develop - ANSWER-prior to birth, produced in the l...
Goal of Transplant - ANSWER--Cure disease 
-Increase disease free survival 
Hematopoiesis - ANSWER--Regulation, production and development of blood 
cells 
-Pluripotent Stem cells 
-Progenitor Stem Cells. 
-Myeloid and lymphoid lineage 
Myeloid progenitor cells mature into: - ANSWER-Megakaryocytes (...
Vista previa 1 fuera de 3 páginas
Añadir al carritoGoal of Transplant - ANSWER--Cure disease 
-Increase disease free survival 
Hematopoiesis - ANSWER--Regulation, production and development of blood 
cells 
-Pluripotent Stem cells 
-Progenitor Stem Cells. 
-Myeloid and lymphoid lineage 
Myeloid progenitor cells mature into: - ANSWER-Megakaryocytes (...
TRANSPLANT PREP REGIMENS - ANSWER-Treatment leading up to 
transplant 
Acronyms: 
Ara-C 
BCNU 
BU 
Cy 
DLT 
SCT 
TBI - ANSWER-Cytarabine 
Carmustine 
Busulfan 
Cyclophosphamide 
Dose limiting toxicity 
DStem cell transplant 
Total body irradiation 
Induction chemotherapy - ANSWER-The first treatment...
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Añadir al carritoTRANSPLANT PREP REGIMENS - ANSWER-Treatment leading up to 
transplant 
Acronyms: 
Ara-C 
BCNU 
BU 
Cy 
DLT 
SCT 
TBI - ANSWER-Cytarabine 
Carmustine 
Busulfan 
Cyclophosphamide 
Dose limiting toxicity 
DStem cell transplant 
Total body irradiation 
Induction chemotherapy - ANSWER-The first treatment...
Immunoglobulins are secreted by which type of cell? 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer - ANSWER-A. B-lymphocyte 
B lymphocytes synthesize and secrete immunoglobulins. 
Which portion of the immunoglobulin activates the complement pathway? 
A. MHC Class I 
B. Fab 
C...
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Añadir al carritoImmunoglobulins are secreted by which type of cell? 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer - ANSWER-A. B-lymphocyte 
B lymphocytes synthesize and secrete immunoglobulins. 
Which portion of the immunoglobulin activates the complement pathway? 
A. MHC Class I 
B. Fab 
C...
What does Red Bone marrow do - ANSWER-Produces Hematopoietic Stem cells 
that create RBC, plt, and WBC found in long and flat bones 
Think: Red like red blood cells 
What does Yellow Bone Marrow do? - ANSWER-Both Yellow marrow and fat 
cells produce stromal stem cells that produce fat, cartilage and...
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Añadir al carritoWhat does Red Bone marrow do - ANSWER-Produces Hematopoietic Stem cells 
that create RBC, plt, and WBC found in long and flat bones 
Think: Red like red blood cells 
What does Yellow Bone Marrow do? - ANSWER-Both Yellow marrow and fat 
cells produce stromal stem cells that produce fat, cartilage and...
Which of the following is an example of a myeloid cell? 
A. Thymus-derived cells (T cells) 
B. Bone marrow-derived cells (B cells) 
C. Monocytes 
D. Natural killer cells - ANSWER-C. Monocytes 
Several factors affect immune reconstitution following hematopoietic stem cell 
transplantation (HSCT). The...
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Añadir al carritoWhich of the following is an example of a myeloid cell? 
A. Thymus-derived cells (T cells) 
B. Bone marrow-derived cells (B cells) 
C. Monocytes 
D. Natural killer cells - ANSWER-C. Monocytes 
Several factors affect immune reconstitution following hematopoietic stem cell 
transplantation (HSCT). The...
A. L. is receiving an autologous transplant. During the stem cell infusion, A. L begins to 
feel chest tightness, flushing and is hypertensive. A.L. is most likely experiencing what 
type of reaction? 
a. Acute hemolytic reaction 
b. Urticarial reaction 
c. Dimethyl sulfoxide toxicity 
d. Anaphylact...
Vista previa 1 fuera de 2 páginas
Añadir al carritoA. L. is receiving an autologous transplant. During the stem cell infusion, A. L begins to 
feel chest tightness, flushing and is hypertensive. A.L. is most likely experiencing what 
type of reaction? 
a. Acute hemolytic reaction 
b. Urticarial reaction 
c. Dimethyl sulfoxide toxicity 
d. Anaphylact...
A. L. is receiving an autologous transplant. During the stem cell infusion, A. L begins to 
feel chest tightness, flushing and is hypertensive. A.L. is most likely experiencing what 
type of reaction? 
a. Acute hemolytic reaction 
b. Urticarial reaction 
c. Dimethyl sulfoxide toxicity 
d. Anaphylact...
Vista previa 1 fuera de 2 páginas
Añadir al carritoA. L. is receiving an autologous transplant. During the stem cell infusion, A. L begins to 
feel chest tightness, flushing and is hypertensive. A.L. is most likely experiencing what 
type of reaction? 
a. Acute hemolytic reaction 
b. Urticarial reaction 
c. Dimethyl sulfoxide toxicity 
d. Anaphylact...
Two types of marrow - ANSWER-red and yellow 
red marrow - ANSWER-thick, blood like material found in flat bones and the ends of 
long bones; location of blood cell formation 
yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long 
bones 
Hematopoietic location through life...
Vista previa 1 fuera de 2 páginas
Añadir al carritoTwo types of marrow - ANSWER-red and yellow 
red marrow - ANSWER-thick, blood like material found in flat bones and the ends of 
long bones; location of blood cell formation 
yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long 
bones 
Hematopoietic location through life...
T.R. is a 28-year-old woman with acute myeloid leukemia in her second complete 
remission who is admitted for a matched unrelated allogeneic stem cell transplantation. 
Her conditioning regimen is as follows: 
Myeloablation (busulfan/cyclophosphamide) and immunosuppression with tacrolimus 
and metho...
Vista previa 2 fuera de 10 páginas
Añadir al carritoT.R. is a 28-year-old woman with acute myeloid leukemia in her second complete 
remission who is admitted for a matched unrelated allogeneic stem cell transplantation. 
Her conditioning regimen is as follows: 
Myeloablation (busulfan/cyclophosphamide) and immunosuppression with tacrolimus 
and metho...
A patient developed type 4 PTLD three years after an allogeneic HSCT. Which of the 
following treatment interventions would the nurse expect an order for? - 
ANSWER-Aggressive chemotherapy 
Red bone marrow produces - ANSWER-hematopoietic stems cells that create red blood 
cells, white blood cells an...
Vista previa 4 fuera de 61 páginas
Añadir al carritoA patient developed type 4 PTLD three years after an allogeneic HSCT. Which of the 
following treatment interventions would the nurse expect an order for? - 
ANSWER-Aggressive chemotherapy 
Red bone marrow produces - ANSWER-hematopoietic stems cells that create red blood 
cells, white blood cells an...
The administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found 
to be a feasible therapeutic option in which EBV mediated-disease process? 
a) Lymphoproliferative disease 
b) Neuroblastoma 
c) Nasopharyngeal rhabdomyosarcoma 
d) Acute lymphocytic leukemia 
A) Lymphoproliferati...
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Añadir al carritoThe administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found 
to be a feasible therapeutic option in which EBV mediated-disease process? 
a) Lymphoproliferative disease 
b) Neuroblastoma 
c) Nasopharyngeal rhabdomyosarcoma 
d) Acute lymphocytic leukemia 
A) Lymphoproliferati...
What type of transplants commonly have PTLD as a secondary malignancy? - 
ANSWER-Allo HSCT with T-cell depleted graft 
Therapies associated with therapy-related acute leukemia and MDS - 
ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , 
radiation, topoisomerase II inhib...
Vista previa 2 fuera de 6 páginas
Añadir al carritoWhat type of transplants commonly have PTLD as a secondary malignancy? - 
ANSWER-Allo HSCT with T-cell depleted graft 
Therapies associated with therapy-related acute leukemia and MDS - 
ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , 
radiation, topoisomerase II inhib...
Myeloid progenitors give rise to which of the following types of cells during 
hematopoiesis? 
A. NK cells 
B. Plasma Cells 
C. Erythrocytes 
D. T lymphocytes - ANSWER-D. T lymphocytes 
Myeloid progenitors give rise to erythrocytes 
Which of the following would be an optimal donor choice for a 26-ye...
Vista previa 2 fuera de 14 páginas
Añadir al carritoMyeloid progenitors give rise to which of the following types of cells during 
hematopoiesis? 
A. NK cells 
B. Plasma Cells 
C. Erythrocytes 
D. T lymphocytes - ANSWER-D. T lymphocytes 
Myeloid progenitors give rise to erythrocytes 
Which of the following would be an optimal donor choice for a 26-ye...
Which of the following medications should a patient taking cyclosporine avoid following 
an allogeneic HSCT? 
A. Torsemide 
B. Bumetanide 
C. Spironolactone 
D. Furosemide - ANSWER-C. Patients taking cyclosporine should avoid potassium 
sparing diuretics such as spironolactone. 
How is bronchiolitis...
Vista previa 2 fuera de 10 páginas
Añadir al carritoWhich of the following medications should a patient taking cyclosporine avoid following 
an allogeneic HSCT? 
A. Torsemide 
B. Bumetanide 
C. Spironolactone 
D. Furosemide - ANSWER-C. Patients taking cyclosporine should avoid potassium 
sparing diuretics such as spironolactone. 
How is bronchiolitis...
Immunoglobulins are secreted by which type of cell? 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer - ANSWER-A. B-lymphocyte 
B lymphocytes synthesize and secrete immunoglobulins. 
Which portion of the immunoglobulin activates the complement pathway? 
A. MHC Class I 
B. Fab 
C...
Vista previa 2 fuera de 13 páginas
Añadir al carritoImmunoglobulins are secreted by which type of cell? 
A. B-lymphocyte 
B. Megakaryocyte 
C. T-lymphocyte 
D. Natural killer - ANSWER-A. B-lymphocyte 
B lymphocytes synthesize and secrete immunoglobulins. 
Which portion of the immunoglobulin activates the complement pathway? 
A. MHC Class I 
B. Fab 
C...
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