PHM240 Exams Pack Questions and Correct Answers | Latest Update | A+

is Meta-analysis is the gold standard for determination of treatment efficacy? Ans: False. A paper looked at the discrepancies between meta-analysis and subsequent large, randomized trials. They state that "Large randomized, controlled trials are generally considered the gold standard in evalu...

Give examples of how drug interactions can be due to interactions at the receptor level. Ans: There are classic examples of ß-blockers inhibiting ß-agonists used to treat asthma leading to serious adverse events. Of course, atropine and other drugs that have anticholinergic effects inhibit ch...

what is the gold standard for the determination of treatment efficacy? Ans: Large randomized, controlled trials. NOT meta-analysis Suicide inhibitor vs competitive inhibtor Ans: Suicide: irreversibly binds to enzymes to form chemically reactive metabolite and permanently inactivates - time depe...

Meta-analysis Ans: A statistical method that combines results from multiple studies to assess treatment effectiveness and draw more reliable conclusions. Dose-response relationship Ans: The correlation between the dosage of a drug and its impact on the body, which may not always follow a line...