NURS 329 - Quiz 1 Questions With Complete Solutions

What is peptic ulcer disease (PUD)? correct answer: *Think erosions or ulcerations (vary in depth & location) -imbalance between mucosal defensive and aggressive factors Where is peptic ulcer disease most common? correct answer: stomach and small intestines (Duodenum) What causes a peptic ulcer disease? correct answer: H. pylori infection, NSAID - Aspirin, cigarettes, alcohol, gastric hyperactivity, duodenal gastric reflux What are some potential complications regarding peptic ulcer disease? correct answer: bleeding, perforation, contents spilling in the peritoneal cavity Someone with PUD makes too much of? correct answer: Gastric acid What helps limit gastric acid in the GI tract? correct answer: -mucus helps so gastric juices doesn't penetrate -Bicarb secretion into mucus What does H. Pylori do? correct answer: -colonizes the stomach and duodenum by taking up the residence in the space between the epithelial cells & mucous barrier -bacteria escapes destruction by acid & pepsin Aggressive factors of ulcers? correct answer: H. pylori, NSAIDs, gastric acid, pepsin, smoking Defensive factors of ulcers? correct answer: mucus, bicarbonate, blood flow, prostaglandins (helps w/ blood clot formation) What are the goals of therapy for PUD? correct answer: -alleviate symptoms (acid reflux, abdominal cramping) -promote healing -prevent reoccurrence Does drug therapy alter the disease process? correct answer: No, it only creates conditions conducive to healing (exception of antibiotics) What are the classes of Anti-Ulcer Drugs? correct answer: -Antibiotics --- Antibacterial -Anti-secretory agents -Anti-secretory Meds that enhance mucosal defense -Mucosal protectants -Antacids A patient has a gastric ulcer, H. Pylori is present, and symptomatic, will pt need to be on antibiotics? correct answer: Yes! We will only put pts on antibiotics if they test positive f