100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Lecture Notes $3.91   Add to cart

Class notes

Lecture Notes

1 review
 20 views  0 purchase
  • Course
  • Institution

Lecture notes of 12 pages for the course Metabolic Pathways at QMUL

Preview 2 out of 12  pages

  • March 5, 2021
  • 12
  • 2020/2021
  • Class notes
  • Main
  • All classes

1  review

review-writer-avatar

By: betulalm • 3 year ago

avatar-seller
Cholesterol and steroids
Learning objectives:

1. Describe in general the 3 stage process of cholesterol synthesis from acetyl CoA.
2. Describe the regulation of cholestrol synthesis
3. Describe the transport of choletrol and TAGs around the body
4. Role of cholestery esters
5. Describe the structure of lipoprotein particles

Why is cholesterol vital?

 Cholesterol has a crucial role in:
- Structure of membranes
- Precursor of steroid hormones
e.g. progesterone
testosterone
estrogen
- precursor bile acid & vitamin D
- its biosynthesis exemplifies a fundamental mechanism for
assembly of extended C skeleton from 5-C units
- regulation of cholesterol synthesis and transport great example
of how biochemistry feeds into medicine




Sources of cholesterol

 cholesterol is an essential molecule but not required in diet because all cells can synthesis
cholesterol from simple precursors.

, De novo cholesterol synthesis

 similar to ketogenic pathway (ketne bodies)
 occurs in cytosol
 requires NADPH and ATP
 highly regulated
 80 % in lives (~1g/d)
 10 % in intestine
 ~5 % in skin
 All of its carbon atoms are provided by a single precursor
- Acetate (as acetyl-CoA)

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller fatima-attia. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $3.91. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

79373 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$3.91
  • (1)
  Add to cart