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opfrissing Histologie pathologie 1
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Pathology 1Introduction
Begrippen (medisch)
- Anamnesis: ziekte geschiedenis
o Auto anamnese: zelf vertellen
o Hetero anamnese: iemand anders verteld
- Anatomy: ana tome = to cut apart
- Physiology: hoe iets functioneerd
- Pathology: ziekte leer, oorzaak -> verloop ziekte
- Autopsie: postmortem examination
- Histology: leer van de weefsels
- Cytology: leer van de cellen
Histology
4 types of tissue
- Epithelial tissue: first layer inside and outside
- Connective tissue: beneath epithelial tissue
- Muscle tissue: hart, skeleton
- Nerve tissue: nerve and nerve cells
Epithelial tissue
cover internal and external surface
functions: protection, filtration, secretion and absorption.
Cell junction
- tight junction
- desmosome
- GAP junction
Form fit function
- Microvilli
- Glands
- Cilia -> trilharen, where movement is necessary (trachea, fallopian tube)
- Stratum corneum
, Classification of epithelia cell shape
- Squamous
- Cuboidal
- Columnar
Classification of layers
- Simple pseudostratified
- Stratified
Simple squamous
- Endothelium
- Mesothelium
- Pericardium
- Air sacs of lungs
o 1 layer for easy exchange substances.
Endothelium -> exchange between cells
Simple cuboidal epithelium -> kidney tubes, Glands
Simple columnar epithelium -> digestive trad (stomach, bowel)
Pseudostratified epithelium -------------------------
looks multi-layered but is a single-layer
one layer (nuclei)
- absorption and secretion -> trachea
- cilia
Stratified squamous epithelium ----------------------------------------------------------------
multi-layered
skin and esophagus (slokdarm)
Transitional epithelium-----------------------------------
- modified stratified squamous
- urinary bladder, ureters, part of urethra.
- Stretching, shape
- Umbrella cells
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