Summary An Approach to Hepatomegaly

An approach to Hepatomegaly:

VITAMIN C

Vascular
Inflammatory (Infectious and non-Infectious)
Trauma/ Toxins
Autoimmune
Metabolic
Idiopathic
Neoplastic



Causes of Hepatomegaly:
Vascular - Right Heart Failure (massive hepatomegaly)
- Tricuspid Regurgitation (pulsatile liver)

Infective: - Hepatitis
(usually causes a mild, - HIV
tender hepatomegaly) - Malaria
- Infective Mononucleosis (EBV)
- CMV

Toxins:
- Alcoholic Liver Disease with fatty infiltrates (causes massive
Alcohol hepatomegaly)

- Alcoholic cirrhosis (initially usually causes a firm and irregular
hepatomegaly)

Autoimmune:
Metabolic:
Idiopathic:
Neoplasms: - Hepatocellular Ca
(usually causes massive - Metastases (most common)
hepatomegaly)
- Leukemia
- Lymphoma