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Samenvatting Hoorcollege diverse tumoren/hematologie testvision Oncologie en complexe zorgverlening
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Hoorcollege diverse tumoren/hematologie testvision Oncologie en complexe zorgverlening
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College “Oncologie diversen/ Hematologie”• Bloed
• Leukemie
• Lymfomen
• Morbus Kahler (multiple myeloom)
• Oncologie diversen (long, maag/ darm)
Functies van Bloed
• Transport van: gassen, voedingsstoffen, afvalproducten, hormonen
• Regulatie pH (zuurgraad, ideale situatie: 7,4)
• Lichaamstemperatuur
• Afweer
• Stolling
Bloed - Samenstelling
Bloed is gemiddeld 8% van
ons lichaamsgewicht.
90% is water!
In bloed zitten de belangrijke eiwitten:
Albumine: zorgen voor de juiste COD
Globuline: dit zijn antistoffen
Fibrinogeen: eiwit die zorgt voor stolling
Plasma
• Vloeibare gedeelte vanbloed
– lichtgeel voor 91% water
• Plasma-eiwitten: 6-8 % (colloidosmotische druk)
Albumin: colloid osmotische druk
Globulines: verschillende soorten
Alfa: transport hormonen en vitaminen beta: ( o.a transferrine: transport ijzer)
gamma: immunoglobulines
Fibrinogeen: stolling
, Bloedcellen
• Rode bloedcellen (erythrocyten)
• Witte bloedcellen (leukocyten)
– Granulocytes
• Neutrophils
• Eosinophils
• Basophils
– Agranulocytes
• Lymphocytes
• Monocytes
• Bloedplaatjes (thrombocyten)
Hematopoiesis – Productie van bloedcellen
In normale bloedsomloop moeten alleen rijpe bloedcellen aanwezig zijn en geen voorstadia,
deze bevinden zich in het beenmerg.
Erythrocyten (rode bloedlichaampjes,
deze hebben geen kern
• Structure
– Biconcave, anucleate
• Components
– Hemoglobin
– Lipids, ATP, carbonic anhydrase
• Function
– Transport oxygen from
lungs to tissues and carbon dioxide from tissues to lungs
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