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Summary WK11Assign. Extention .docx NURS 6521 Off Label Drug Use in Pediatrics Acute Adult and Gerontology Nurse Practitioner, Walden University NURS 6521N: Advanced Pharmacology Off Label Drug Use in Pediatrics Off label drug use is becoming more common,

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WK11Assign. Extention .docx NURS 6521 Off Label Drug Use in Pediatrics Acute Adult and Gerontology Nurse Practitioner, Walden University NURS 6521N: Advanced Pharmacology Off Label Drug Use in Pediatrics Off label drug use is becoming more common, mainly due to the lack of pediatric- specif...

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wk11assign extention docx nurs 6521 off label drug use in pediatrics acute adult and gerontology nurse practitioner
walden university nurs 6521n advanced pharmacology off label drug use in p

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Purdue University
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NURS 6521

Off Label Drug Use in Pediatrics

Acute Adult and Gerontology Nurse Practitioner, Walden University

NURS 6521N: Advanced Pharmacology

Off Label Drug Use in Pediatrics

Off label drug use is becoming more common, mainly due to the lack of pediatric-

specific data regarding the dosing efficacy and safety of medications regularly prescribed to

children. This narrative will explain the circumstances under which children should be prescribed

drugs for off-label use. Also, the description of strategies to make the off-label use and dosage of

drugs safer for children from infancy to adolescence.

Circumstance Children are Prescribed Off-Label Drugs

Off-label drugs are often used when the benefit outweighs the risk of the medication

being prescribed (Arcangelo et al., 2017). There are several circumstances where off-label drugs

are prescribed for pediatrics such as, antibiotic therapy for respiratory infection of prophylactic

for surgery, antihistamine use for asthma and respiratory infections, analgesics, antiemetics,

depressants, and psychotropics for mental illness (Cuzzolin, Zaccaron, Fanos, 2003).some of

those drugs includes drug like amoxicillin and antihistamines like mequitazine and desloratadine

which the benefit outweighs the risk as there is minimal risk associated with these drugs

(Palmaro et al., 2014).

Strategies for Safer Off-Label Drug Use and Dosage

As with any prescription drug safety consist of continued and frequent monitoring and

come with guidelines to follow, however, most drugs do not have guidelines on pediatric use

only approximates based on the child’s body surface area, weight, and other factors (Rosenthal &

Burchum, 2018). Drugs such as like prednisone and dexamethasone have the potential to impede

normal development in pediatrics as well as cause behavioral and cognitive changes

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Summary WK11Assign. Extention .docx NURS 6521 Off Label Drug Use in Pediatrics Acute Adult and Gerontology Nurse Practitioner, Walden University NURS 6521N: Advanced Pharmacology Off Label Drug Use in Pediatrics Off label drug use is becoming more common,

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