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Samenvatting artikelen 3e deeltentamen: CVA en Parkinson

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Een samenvatting van de 6 artikelen van de onderdelen: CVA en de ziekte van Parkinson. De samenvatting is vooral gefocust op de inhoud van de studie, resultaten, discussie en conclusie.

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  • May 27, 2021
  • 12
  • 2020/2021
  • Summary
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Samenvatting artikelen
deeltentamen 3
Inhoud
CVA.........................................................................................................................................................2
Kwakkel, G., Winters, C., van Wegen (2016). Effects of Unilateral Upper Limb Training in Two
Distinct Prognostic Groups Early After Stroke: The EXPLICIT-Stroke Randomized Clinical Trial..........2
Langhorne, P., Bernhardt, J., Kwakkel, G.(2011). Stroke rehabilitation..............................................3
Dina Pogrebnoy, Amy Dennett (2020). Exercise Programs Delivered According to Guidelines
Improve Mobility in People With Stroke: A Systematic Review and Meta-analysis............................4
Parkinson’s Disease................................................................................................................................6
Hirsch MA, van Wegen EEH, Newman MA, Heyn PC. (2018). Exercise-induced increase in brain-
derived neurotrophic factor in human Parkinson's disease: a systematic review and meta-analysis.
............................................................................................................................................................6
Nieuwboer A, Kwakkel G, Rochester L, et al. (2007). Cueing training in the home improves gait-
related mobility in Parkinson’s disease: the RESCUE trial...................................................................7
Mirelman, A., Bonato, P., Camicioli, R., Ellis, T. D., Giladi, N., Hamilton, J. L., ... & Almeida, Q. J.
(2019). Gait impairments in Parkinson's disease................................................................................9

, CVA
Kwakkel, G., Winters, C., van Wegen (2016). Effects of Unilateral
Upper Limb Training in Two Distinct Prognostic Groups Early After
Stroke: The EXPLICIT-Stroke Randomized Clinical Trial.
 Favourable prognosis-> mCIMT
 Unfavourable prognosis-> EMG-NMS

Testen
1. Primair: ARAT: test de ability om grote bewegingen te maken en om dingen op te
pakken, los te laten in verschillende vormen etc.
2. Secundair: SIS-hand: evaluatie hoe de patiënt taken met de getroffen arm ervaart van
"helemaal niet moeilijk" tot "moeilijk"
3. Secundair: FMA-UE: evalueert het vermogen om armbewegingen te maken buiten
het synergisch patroon

Resultaten
mCIMT
 ARAT
o Significant tijd-groep interactie effect na 5 en 12 weken na de stroke in
vergelijking met normale zorg
 SIS-hand:
o Significant tijd-groep interactie effect na 8 weken na de stroke in vergelijking
met normale zorg
 FMA-UE: The Fugl-Meyer Assessment for upper extremity


EMG-NMS
 ARAT
o Geen significant effect
 SIS-hand

Discussie
 mCIMT ARAT: effecten bleven niet tot 26 weken, waarschijnlijk omdat het effect
vertraagd was bij de normale zorg groep met een gunstige prognose
o Misschien hogere dosis?
 mCIMT: positieve veranderingen in capaciteit van de bovenste ledenmaten, vooral
door het aanleren van adapieve bewegingsstrategieen.
 Het is niet de neurologische stoornis die wordt verholpen, maar een optimale manier
van bewegen. Dit werd duidelijk nadat er een effect bij ARAT in de chronische fase na
de stroke was gevonden, maar niet bij de FMA-UE

Implicaties
 Hoeveelheid dosis tussen interventie en usual care groep kwam niet overeen
 Restricted patient, maar dit verhelpt waarschijnlijk niet de negatieve resulaten
 Lack of homogeneity between subjects

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