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Samenvatting Secundaire metabolieten en hun werking (1036FBDFAR)
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Een samenvatting van alle secundaire metabolieten en hun geneeskundige werking/doeleinden. Gegeven door prof. dr. Pieters
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SECUNDAIRE METABOLIETEN EN HUN GENEESKUNDIGE DOELEINDENPolyketiden, fenylpropaanderivaten en combinatieproducten
Statines
● Cholesterolverlagend
Aspirine / Acetylsalicylzuur
● Pijnstillend
● Koortsverlagend
● Ontstekingsremmend
Naftochinonen
● Anti-malaria
Lignanen
● Anti-kanker: inhibitie van DNA-topoisomerase (replicatie en transcriptie DNA)
Terpenen
Sesquiterpenen (bv: Artemisinin)
● Anti-malaria
Paclitaxel (Taxol)
● Anti-kanker
Echte Kamille
● Ontstekingsremmend
● Maag- / darmwerking bevorderen
● Cosmetica: blonderen van het haar
Triterpenen (bv: Digoxine)
● Sterkte hartcontracties verhogen
○ “Hartwerkzame glycosiden”
Alkaloïden
Tropaanalkaloïden
● Parasympathicolytica
○ gladde spiercellen relaxeren
○ tegen krampen in gastro-intestinale stelsel of urinewegen
○ bronchiën / luchtwegen doen dilateren bij astmatische aandoeningen
○ effectief tegen reisziekte
Medicinale planten // Dr. Prof. Luc Pieters // 2020 - 2021
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