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Samenvatting Hoorcollege 22 excretiesysteem 1
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Hoorcollege 22 excretiesysteem 1Functies nieren
- Homeostatisch regulatie: extracellulair vloeistofvolume, osmolariteit, ionbalans en pH.
- Excretie: metabolisch afval en xenobiotica.
- Productie hormonen: EPO (erythryopoietin), renin (RAAS), prostaglandine, calcitrol (vitamine D).
Evolutie nieren
Pronephros Mesonephros Metanephros
Vissen, amfibiëen en reptielen hebben soortgelijke nieren met kapsel van Bowman, proximale tubulus,
intermediair segment en distale tubulus.
Vogels (hebben beiden) en zoogdieren kunnen urine concentreren en hebben nog een deel genaamd de lis
van Henle.
Dolfijn Os Mens Paard
De nier van de rat lijkt heel erg op die van de mens.
Rechts algemene anatomie belangrijk bij fysiologie.
Vanaf de ureter gaat de urine naar de urineblaas.
In de cortex zitten de glomeruli en in het merg de lis van
Henle.
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