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Dermatologie: volledige samenvatting + examenvragen

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Volledige samenvatting van het vak Dermatologie (voor de studie Tandheelkunde), gedoceerd door professor De Haes en Garmyn. Een bundeling van de slides en alle online lessen, inclusief de examenvragen steeds bij de bijhorende tekst. Slaag je tweede master met onderscheiding!

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  • August 1, 2021
  • 62
  • 2020/2021
  • Summary
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DERMATOLOGIE
PETRA DEHAES




0

,INHOUD



H1: Anatomie en fysiologie van de huid (niet kennen).............................................................................................................................................. 7

Huid ................................................................................................................................................................................................................................... 7

Epidermis ...................................................................................................................................................................................................................... 7

Dermis........................................................................................................................................................................................................................... 8

Subcutis (variabele dikte) ............................................................................................................................................................................................ 8

Epidermale basale membraan zone ............................................................................................................................................................................ 8

Huidadnexen ..................................................................................................................................................................................................................... 8


H2: Onderzoek van de huid (niet kennen)................................................................................................................................................................. 9

Primaire en secundaire efflorescenties .................................................................................................................................................................... 9

Rangschikking, vorm, oppervlak, lokalisatie ......................................................................................................................................................... 11

Rangschikking, vorm, oppervlak .......................................................................................................................................................................... 11
Lokalisatie ................................................................................................................................................................................................................... 11


H3: Eczeem ............................................................................................................................................................................................................. 12

Inleiding en classificatie ................................................................................................................................................................................................. 12

Seborrhoïsch eczeem ................................................................................................................................................................................................. 12

Atopisch eczeem ........................................................................................................................................................................................................ 13


H4: Acne en rosacea ............................................................................................................................................................................................... 15

Acne vulgaris ................................................................................................................................................................................................................... 15

Rosacea ........................................................................................................................................................................................................................... 16


H5: Lichen planus .................................................................................................................................................................................................... 17

Lichen planus .................................................................................................................................................................................................................. 17


H6: Candidosis ........................................................................................................................................................................................................ 19

Candidosis ....................................................................................................................................................................................................................... 19


H7: Psoriasis ............................................................................................................................................................................................................ 21

Psoriasis .......................................................................................................................................................................................................................... 21


H8: Orale erosieve mucosale letsels en aften ......................................................................................................................................................... 25

Differentiële diagnose .................................................................................................................................................................................................... 25

Infecties ...................................................................................................................................................................................................................... 25

Huidziekten................................................................................................................................................................................................................. 26

Medicatie .................................................................................................................................................................................................................... 26

Maligne letsels............................................................................................................................................................................................................ 27

Trauma ........................................................................................................................................................................................................................ 27

Aften en recidiverende afteuze stomatitis (ras) ....................................................................................................................................................... 27



1

,H9: Contactdermatitis, stomatitis en cheilitis ......................................................................................................................................................... 29

Contactallergische reacties: algemeen ......................................................................................................................................................................... 29

Onmiddellijke overgevoeligheidsreactie of type i allergische reactie .......................................................................................................................... 30

Vertraagde overgevoeligheidsreactie of type iv allergische reactie ............................................................................................................................ 31

Allergische contact cheilitis en dermatitis ................................................................................................................................................................ 31

Allergische contactstomatitis .................................................................................................................................................................................... 33

Tandheelkundige materialen ..................................................................................................................................................................................... 35

Intermezzo.................................................................................................................................................................................................................. 37


H10: Bulleuze dermatosen ...................................................................................................................................................................................... 38

Inleiding........................................................................................................................................................................................................................... 38

Congenitale bulleuze dermatosen ................................................................................................................................................................................. 38

Verworven bulleuze dermatosen ................................................................................................................................................................................... 39

Pemphigus vulgaris .................................................................................................................................................................................................... 40

Pemphigus foliaceus .................................................................................................................................................................................................. 42

Bulleus pemphigoid.................................................................................................................................................................................................... 43

Cicatricieel pemphigoid = mucosaal membraan pemphigoid ................................................................................................................................. 44

Epidermolysis bullosa acquisita ................................................................................................................................................................................. 44


H11: Bacteriële infecties van de huid ...................................................................................................................................................................... 45

Verdedigingsmechanismen tegen bacteriële infecties ................................................................................................................................................. 45

Bacteriële huidinfecties .................................................................................................................................................................................................. 45

Epidermis .................................................................................................................................................................................................................... 46

Huidaanhangsels/haarfollikels................................................................................................................................................................................... 47

Diepere huidlagen ...................................................................................................................................................................................................... 49


H12: Virale infecties van de huid............................................................................................................................................................................. 50

Humane herpesvirussen ................................................................................................................................................................................................. 50

Herpes simplex virus .................................................................................................................................................................................................. 50

Varicella zoster virus .................................................................................................................................................................................................. 50

Humane papillomavirussen ........................................................................................................................................................................................... 53

Molluscipoxvirus ............................................................................................................................................................................................................. 53


H13: Epidermale tumoren, goedaardige pigmentletsels en maligne melanoom .................................................................................................... 54

Epidermale tumoren van de huid .................................................................................................................................................................................. 55

Premaligne epidermale afwijkingen.......................................................................................................................................................................... 55

Maligne epidermale tumoren ................................................................................................................................................................................... 56

Goedaardige pigmentletsels en maligne melanoom .................................................................................................................................................... 58

Goedaardige pigmentletsels...................................................................................................................................................................................... 58

Maligne melanoom .................................................................................................................................................................................................... 60




2

, EXAMENVRAGEN DERMATOLOGIE


EXAMENVRAGEN

OPEN VRAGEN


• Bespreek recurrente afteuze stomatitis (RAS): kliniek en behandeling. (2021) (2020) (2019)
• Vergelijk acne en rosacea: kliniek en behandeling. (2019)
• Bespreek rosacea en periorale dermatitis. (2019)
• Vergelijk lichen planus en pemphigus vulgaris. (2019)
• Vergelijk lichen en candida. (2018)
• Bespreek uitgebreid afteuze stomatitis. (2018)
• Bespreek HSV. (vorige jaren)
• Bespreek bulleuze dermatosen. (vorige jaren)
• Bespreek lichen planus. (vorige jaren)



MEERKEUZEVRAGEN


• Irritatie testen met tandpasta (2021): semi open testen.
• Precursor maligne melanoom (2021): dysplastisch naevus.
• Maligne melanoom (2021): bij ouder dan 70, maculaire vlek, door chronische blootstelling.
• Geen mucosale erosie (2021): pemphigus foliaceus.
• Pemphigus foliaceus (2021): anti desmogleïne 1.
• Wat is waar over psoriasis? (2021): typerend schilferend.
• Erosief lichen planus (2021): lijkt op pemphigus vulgaris, komt veel cutaan voor.
• Waar komt seborrhoïsch eczeem voornamelijk voor? (2021): presternaal, nasolabiale plooien, haargrens.
• Wat is het grootste probleem bij acne? (2021): keratose stoornis.
• Welk type allergie is allergische contact urticaria? (2021): type I allergie.
• Hoe diagnose stellen MM pemphigoïd? (2021): bioptie en DIF
• Mogelijke oorzaken atrofische glottitis? (2021): candida, B12-tekort.
• Welke kliniek hoort bij atopisch eczeem? (2021): familiale VG, voorkeursplaatsen, extreme jeuk
• Wat is de DD van leukoplakie? (2021): lichen planus, candida, niet invasief SCC.
• Welke medicatie bij herpes zoster? (2021): acyclovir 5x 800mg/dag
• Wat zijn de risicofactoren van lichen planus? (2021): contactallergie, irritatie en geneesmiddelen.
• Wat is agressief SCC (2021): mucosaal SCC, actinische keratose, zonblootgestelde.
• Wat is besmettelijk? (2021): impetigo.


• Wat is waar over atopisch eczeem? (2021)
a) Koemelkallergie kan verdwijnen na een leeftijd van 2 jaar
b) Pindanotenallergie kan verdwijnen na een leeftijd van 2 jaar
c) 15% van de mensen groeit eroverheen na 45 jaar
d) Komt vooral voor bij 70 jarigen




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