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Summary 3.6 Problem 1

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summary for 3.6 problem 1 neuropsychology ( unfortunately, I don't have summaries for the rest of the problems in this course, you can look at other stuvia notes for that, good luck!)

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  • August 13, 2021
  • 30
  • 2021/2022
  • Summary
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Problem 1

Learning Goals
To learn the brain anatomy of the parietal and occipital lobe:
- Which brain areas are located in the parietal lobe and which in the occipital lobe?
- Which are the main functions of the parietal and occipital lobe?
- What are the basal ganglia and which functions do they have?
To learn which neuropsychological disorders are associated with lesions of the parietal and
occipital lobe:
- Which neurological disorders are provoked by lesions of the parietal lobe and which
by the lesions of the occipital lobe?
- Which are the symptoms of the aforementioned neurological disorders?


TOPIC 1 – PERCEPTON AND MOTOR SYSTEMS
Chapter 9 – Organization of motor system (232-250)
Neocortex: initiating movement
- posterior cortex specifies movements goals and sends sensory information into the
frontal regions
o automatic movements take a more direct route and the premotor and
primary motor cortex execute the
action
o movements requiring conscious control
take indirect routes, the temporal and
prefrontal cortices make decisions first,
and then premotor and primary motor
cortices execute movements
- from the instructions of the posterior cortex,
the PFC generates plans for movements
- the premotor cortex (Broadmann’s area 6,
supplementary) houses a movement repertoire
-lexicon-, it recognizes other’s movements and
selects similar or different actions
- the primary motor cortex (M1 or Brodmann’s
area 4) consists of more elementary
movements including hand and mouth movements
- hierarchical control of movement:
o tap a finger: S1, M1
o sequence of finger movements: S1, M1 and premotor
o finger to navigate a maze: prefrontal, temporal and parietal
cortex
Motor homunculus (little human) by Penfield:

, - a homunculus spread out across the motor cortex
- each hemisphere contains an almost mirror image representations of this
homunculus
- also located a secondary homunculus in the supplementary premotor cortex
- motor homunculus is upside down relative to the actual body and the arrangement
of body parts is different from a real body
- it has disproportionate relative sizes compared to real sizes: large hands, especially
large thumb, large lips and tongue  precise fine motor control over those
- motor map was constructed from electrical stimulation
- new technology has shown that there may be many more homunculi within the
motor and premotor cortices
- multiple representation:
o finger movements can be obtained from many points, not just one
o finger movement points also elicit movements of other parts

Natural movement categories
- stimulation elicits ethological categories of movements that monkeys use in everyday
activities e.g. hand moves to mouth and mouth opens
- but movements evoked by stimulation lack flexibility, when there’s an obstacle the
hand hits the obstacle
- many cortical maps of the body exist and each map represents a different action,
spatial location and function
- whole-body movements are represented in the pre-motor cortex and the more
discrete movements in the motor cortex
Visual-parietal motor connections

, - functional movements can be elicited from the parietal cortex too
- the motor cortex and the parietal cortex have dense anatomical connections
o sensory information about a target is sent to the motor cortex
o the visual cortex has to identify the object (extrinsic and intrinsic properties)
and its location
o the visual cortex instructs the parietal arm region about the location and hand
region about the shape
o the parietal region has sensory receptors that will be activated when the
object is contacted
o the parietal region connects to the motor cortex region that will produce
movement over descending pathways
- connections from visual to parietal to motor cortex create a dual pathway that
produce action to grasp an object
- various combinations of parietal-to-motor cortex pathways underlie the complexity
of our movements
The movement Lexicon
- humans have a lexicon, or repertoire of movement categories
- by 3 months most healthy babies start to use the pincer grip
- most primate species use the same grip
- people who have small lesions of motor cortex around the thumb region have
weakness in the thumb and the arm  lesions impair coordinator action of reaching
for and grasping, not individual digit muscles
- skilled movements are encoded in neural connections as basic movement patterns,
they are not learned
- premotor and primary motor cortex share a common movement lexicon and the
repertoire of premotor cortex is more complex than M1
- damage to premotor cortex doesn’t cause muscle weakness but disrupts more-
complex movements
- premotor cortex organizes whole-body movements more than M1
- basic movements elicited in the motor cortex can be extended to other actions
through learning by recruiting neural circuitry
- experiment with monkey:
o before movements: neural activity increases in the motor cortex

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