Summary
samenvatting hoorcollege 4
- Course
- Institution
het gaat om het hoofdstuk Parkinson
[Show more]
Seller
Followjulievancalster
Content preview
HC 4: Parkinson1. Inleiding: voorkomen van ziekte van Parkinson
• Voorkomen van ziekte van Parkinson = primair neurodegeneratieve aandoening (=
geen duidelijke oorzaak hebben + aftakeling van het hersenweefsel)
• Pathologisch = selectieve degeneratie van de dopaminerge neuronen in de substantia
nigra
• Lewy-bodies = insluitsels van alfa-synucleine
• Idiopathische ziekte van Parkinson VS secundair parkinsonisme
o Neuroleptica
o Cinnarizine De medicatie bij secundair
o Flunarizine parkinsonisme
o Vasculair
• Prevalentie
o 0,3% in de algemene populatie
o 1,6% in 65+
o 10% in 80+
o Begin tussen 50 en 70 jaar
• Klinische diagnose = motore symptomen = tremor – akinesie – rigiditeit
• Ondersteund door niet-motore verschijnselen (beeldvorming) + positief effect van
R/L-Dopa (= voorloper van Dopamine → L-Dopa kan hersenvlies doorbreken en
dopamine kan dat niet)
2. Motorische verschijnselen
2.1. Rusttremor
• Beven = rust-tremor van de ledematen
2.2. Bradykinesie
• Bewegingsarmoede = akinesie (traagheid)
• Traagheid, minder spontane bewegingen
• Verlies van spontane mimiek aangezicht
• Minder armzwaai bij het stappen
2.3. (Tandrad)rigiditeit
• Stijfheid = rigiditeit
• Voorovergebogen houding
• Last van fijne bewegingen (motoriek)
2.4. Anderen
• Moeilijk opstaan
• Draaien in bed
• Schrijfstoornis
• Minder stem
• Minder slikken → speekselvloed kan ontstaan
1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller julievancalster. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $6.95. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
53068 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now