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FA-MA103 Individuele Productzorg, Samenvatting

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In deze samenvatting worden de leerdoelen per thema uitgewerkt, die gegeven zijn in de cursuswijzer van FA-MA103 en de werkcolleges. De samenvatting begint met een hoofdstuk met algemene informatie: wat er op een etiket moet staan, omrekenen en factoriseren. Daarna wordt de leerstof uit de werk...

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  • October 22, 2021
  • 58
  • 2021/2022
  • Summary

1  review

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By: ihds • 2 year ago

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FA-MA103
Individuele Productzorg
Samenvatting

,Inhoud
Leerdoelen....................................................................................................................................................... 5
Leerdoelen algemeen .................................................................................................................................. 5
Leerdoelen specifiek.................................................................................................................................... 5
Leerdoelen praktische vaardigheden .......................................................................................................... 5
Algemeen ........................................................................................................................................................ 6
Etiket samenstelling vermelden .................................................................................................................. 6
Farmacon omrekenen met als (casus uit FA-BA202) .................................................................................. 6
Factoriseren voor geadsorbeerd water (voorbeeld kennisbank) ................................................................ 7
Aseptische handelingen (VTGM) ..................................................................................................................... 8
Leerdoelen specifiek uit OB1....................................................................................................................... 8
Aspetische handelwijze ............................................................................................................................... 8
Eisen steriele preparaten ............................................................................................................................ 8
Eisen grondstoffen, uitgangsmaterialen, ruimten en personeel ................................................................ 9
Grondstoffen ........................................................................................................................................... 9
Uitgangsmaterialen ................................................................................................................................. 9
Ruimten en apparatuur ........................................................................................................................... 9
Personeel ............................................................................................................................................... 10
Productbescherming en houdbaarheid..................................................................................................... 11
Parenteralia ................................................................................................................................................... 13
Leerdoelen uit OB2.................................................................................................................................... 13
Leerdoelen uit OB6.................................................................................................................................... 13
Samenstelling ............................................................................................................................................ 13
Formulering parenterale depotpreparaten .............................................................................................. 14
Kwaliteitseisen water ................................................................................................................................ 15
Isotonie...................................................................................................................................................... 15
Iso-osmotisch ........................................................................................................................................ 15
Hyperosmotisch..................................................................................................................................... 16
Hypo-osmotisch..................................................................................................................................... 16
Berekenen van de isotonie .................................................................................................................... 16
Hulpstoffen................................................................................................................................................ 17
Rectaal ........................................................................................................................................................... 19
Leerdoelen uit OB3.................................................................................................................................... 19
Anatomie en fysiologie MDK ..................................................................................................................... 19
Rectaal Vs. Oraal ....................................................................................................................................... 20
Zetpillen..................................................................................................................................................... 21
Zetpilbasis.............................................................................................................................................. 21
Deeltjesgrootte...................................................................................................................................... 22
Hulpstoffen ............................................................................................................................................ 22

2

, Rekenen aan zetpillen ........................................................................................................................... 23
(micro)klysma ............................................................................................................................................ 23
Restvolume............................................................................................................................................ 24
Algemene eisen klysma ......................................................................................................................... 24
Hulpstoffen ............................................................................................................................................ 25
Vloeibare preparaten .................................................................................................................................... 26
Leerdoelen uit OB4.................................................................................................................................... 26
Kenmerken vloeibare toedieningsvormen ................................................................................................ 26
Oplossing ............................................................................................................................................... 27
Suspensie ............................................................................................................................................... 27
Solubilisatie ........................................................................................................................................... 27
Emulsie .................................................................................................................................................. 27
Oplosbaarheid verhogen ........................................................................................................................... 28
Fysisch-chemische achtergronden ............................................................................................................ 30
Suspensies ............................................................................................................................................. 30
Oplossingen ........................................................................................................................................... 32
Solubilisaten en emulsies ...................................................................................................................... 32
Vriesdrogen / lyofiliseren ...................................................................................................................... 34
BCS............................................................................................................................................................. 35
Bio-equivalentie ........................................................................................................................................ 35
Geneesmiddelen toedienen via sonde ...................................................................................................... 36
Soorten sondes ...................................................................................................................................... 36
Sonde materiaal .................................................................................................................................... 37
Oraal vast ...................................................................................................................................................... 38
Leerdoelen uit OB5.................................................................................................................................... 38
Immediate release tabletten ..................................................................................................................... 38
Modified release tabletten........................................................................................................................ 38
Verlengde- Vs. Gereguleerde afgifte ..................................................................................................... 38
Matrixsysteem ....................................................................................................................................... 38
Osmotische pomp - OROS technologie ................................................................................................. 38
Kappen en capping van tabletten ............................................................................................................. 40
ARLE- ‘flip-flop’ kinetiek ............................................................................................................................ 40
Capsules bereiden ..................................................................................................................................... 40
Berekening capsules; eindcontrole ....................................................................................................... 40
Hulpstoffen................................................................................................................................................ 41
Dermatica ...................................................................................................................................................... 42
Leerdoelen uit OB7.................................................................................................................................... 42
Anatomie en fysiologie van de huid .......................................................................................................... 42
Dermatica bij verschillende huidtypes ...................................................................................................... 43


3

, Afgifte van farmaca uit dermatica............................................................................................................. 45
Rekenvoorbeeld met de RPI .................................................................................................................. 47
Penetratie bevorderende stoffen.............................................................................................................. 47
Corticosteroïden bij huidaandoeningen.................................................................................................... 48
KNO oculair en luchtwegen ........................................................................................................................... 50
Leerdoelen uit OB8.................................................................................................................................... 50
Anatomie en fysiologie; keel, neus, oor, oog en luchtwegen ................................................................... 50
Keel ........................................................................................................................................................ 50
Neus....................................................................................................................................................... 51
Oor......................................................................................................................................................... 52
Oog ........................................................................................................................................................ 52
Luchtwegen ........................................................................................................................................... 53
Toedieningsvormen voor het oog ............................................................................................................. 55
Toedieningsvormen voor keel, neus en oor .............................................................................................. 55
Keel ........................................................................................................................................................ 55
Neus....................................................................................................................................................... 55
Oor......................................................................................................................................................... 57
Toedieningsvormen voor pulmonale toediening ...................................................................................... 57
Hulpstoffen................................................................................................................................................ 57
Oordruppels .......................................................................................................................................... 57



In deze samenvatting worden de bereidingswijze uit de LNA niet omschreven. Ook worden niet per
toedieningsvorm de IPC’s nader uitgelicht. Raadpleeg voor de IPC’s en de eindcontroles per
toedieningsvorm FA-MA106 Geneesmiddelontwerp samenvatting.
Ook wordt er in deze samenvatting diverse malen verwezen naar FA-BA305 Huidaandoeningen
samenvatting.




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