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Samenvatting Fysiopathologie en ziekteleer (Behaald Resultaat: 16/20): diabetes type 1 $6.97
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Samenvatting Fysiopathologie en ziekteleer (Behaald Resultaat: 16/20): diabetes type 1
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  • Course
  • Fysiopathologie En Ziekteleer
  • Institution
  • Universiteit Antwerpen (UA)

Dit document bevat alles van wat je moet kennen over diabetes 1: Alles van wat er in de les gezegd is door de prof staat als notitie bij de slide geschreven. Leer dit en je bent er zeker door (Behaald Resultaat: 16/20).

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Document information

  • November 5, 2021
  • 15
  • 2021/2022
  • Summary

Subjects

  • diabetes 1
  • diabetes
  • 3e ba bmw
  • bmw
  • biomedische wetenschappen
  • atero
  • atherosclerose
  • diabetes
  • longen
  • hart
  • nieren
  • hartfalen
  • fysiopatho
  • 2021 2022
  • 2020 2021
  • 2019 2020
  • examenvrag
  • fysiopathologie en ziekteleer

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  • Universiteit Antwerpen (UA)
  • Biomedische Wetenschappen
  • Fysiopathologie En Ziekteleer
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Endocriene pancreas &
diabetes mellitus:
fysiologie & fysiopathologie


Prof dr C. De Block
Prof dr L. Van Gaal
BMW (UA), november 2008




Eilandjes van Langerhans



• ~1-1.5 miljoen eilandjes van Langerhans
• = 1-1.5% vd pancreasmassa
• elk eilandje bevat ~2500 cellen,
bestaande uit 4 types:
– 60-75% betacellen: insuline
– 20-25% alfacellen: glucagon
– 4% deltacellen: somatostatine
– 2% PP of F-cellen: pancreatic
polypeptide




1

, Biosynthese van insuline
Insuline gen


• gen op chromosoom 11


ruw endopl
reticulum




PreProInsuline




Golgi apparaat


Cleavage site Secretoire
granules

B keten
• C-peptide kan gebruikt worden
als merker voor endogene
insulinesecretie

A keten




2

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