Cardiovasculair Stelsel, Ademhaling, Nier En Urinewegen (D001943)
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Histologie AJ 2021-2022
Histologie van het urinair systeem
1. Inleiding
Nieren:
§ Regulatie van water- en elektrolytenbalans en zuur-base balans
§ Excretie van metabole afvalproducten met overmaat water en elektrolyten in urine
§ Excretie van bioactieve substanties
§ Secretie van renine: regulatie van de arteriële bloeddruk
§ Secretie van erythropoietine: stimulatie van RBC productie
§ Omzetten van de pro-vorm van vit D tot de actieve vorm
§ Gluconeogenese tijdens vasten
De nieren liggen retroperitoneaal (omgeven door perirenaal vet waarin ook bijnieren liggen)
Fibreus nierkapsel
Mediale zijde = hilus: a. renalis, v. renalis, nierbekken of pelvis, lymfevaten en zenuwen
gelegen in de niersinus
§ De niersinus is gevuld met vet dat in continuïteit is met het perirenaal vet)
Ureter à nierbekken à 2-3 calices majores à calices minores
Medulla:
§ Pyramiden
o 8-18
o Basis tegen cortex/corticomedullaire junctie
o Top = papillen à komt uit in calix minor
§ Nierkolommen van Bertin
o = strengen vanuit de cortex
o Scheiden pyramiden van elkaar
§ Lobus = pyramide + cortexweefsel rondom en aan basis
Cortex:
§ Mergstralen van Ferrein
§ Lobulus = cortexgebied dat mergstraal omgeeft
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