Gastrin Enzyme Stomach: G cell stimulates secretion of
Fundus/body pepsinogen and H+
Pepsin(ogen) Endopeptida Chief cells pH in stomach makes this
se to pepsin which does the
primary structure protein
digestion (but pepsin is
always present in
stomach)
Lipase Enzyme Chief cells triglyceride digestion (10%
is now free FA’s); free FA
in stomach stimulate
duodenum to produce
CCK
H+ Acid Parietal < pH; protein digestion
cells
IF (intrinsic Enzyme Parietal binds with vitamin B12 in
factor) cells duodenum to be absorbed
in ileum together and
stored in liver
Mucus Slime Surface/ lubrication
neck cells
Ghrelin (growth) made hungry hormone, growth
hormone: from DNA hormone; made when
very small fasting and <BMI.
protein and
, HCI acid conversion of pepsinogen
to pepsin, killing bacteria,
optimize pH
Somatostatin ? D cell sensor when pH is too low;
the D cell starts
somatostatin production;
which binds to G cell;
which then stops gastrin
production; which stops
acid production.
Trypsin Endopeptida Pancreas: is activated by
se Acinus enterokinase at brush
border; does protein
digestion + active trypsin
makes all digestive
proenzymes into active
enzymes.
Monitor peptide Amino acid - monitoring protein
digestion in duodenum: as
long as it’s active it
activates the cells to
release CCK (if trypsin
does a good job CCK
production stops).
Amylase Enzyme CHO digestion
Lipase Enzyme fat digestion
Phospholipase Enzyme fat digestion
Chymotrypsin Endopeptida protein digestion
se
Elastin Endopeptida digestion
se
Dipeptidase Enzyme protein digestion
Disaccharidase Enzyme digestion
HCO3 Enzyme Pancreas: secretin and Ach in the
(bicarbonate) Ductule ductule are stimulating to
release bicarbonate when
active digestive enzymes
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