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Samenvatting : vaatstelsel

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Samenvatting : vaatstelsel

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  • January 6, 2022
  • 3
  • 2018/2019
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VAATSTELSEL
HARTWAND
Myocardium = hartspierweefsel
Dun laagje bindweefsel bekleed binnen en buitenzijde myocardium
Endocarium: losmaziger langs binnenkant + bekledende cellaag = endotheel
Epicardium: densere langs buitenkant + bekledende cellaag = mesotheel

 Hartwand elastische door elastische vezels in myocardium
 Thv kleppen: hartwand verstevigd door collagene vezels  hartskelet
 Hartkleppen = derivaten v/h endocarium  uit bindweefselig inwendige, met endotheel

MYOCARDIUM:
 Rijk aan bloedvaten  coronaire bloedvaten
 bloedvaten tussen bundels hartspiervezels/ myocardiocyten  bundels van Henle  gevuld met
losmazig bindweefsel

IMPULSGELEIDEND STELSTEL. PURKINJECELLEN
MYOCARDIOCYTEN
Signaal  SA- knoop  AV- knoop  bundels van His  purkinjevezels  hartspiervezels
PURKINJEVEZELS
 Groter en minder langwerpig dan hartspiervezels
 Grote hoeveelheden glycogeen
 Geen myofibrillen meer  niet contractiel
 Vertonen geïntercaleerde schijven
 LM: bleek

HARTSPIERWEEFSEL
Enkel aanwezig in myocardium


HARTSPIERVEZELS: MYOCARDIOCYTEN
 Dwarsgestreept (zoals skeletspiervezels)
 Synctiaal karakter  liggen op centrale as
 Centraal “dik” + aan weerszijde korte uitlopers  vorming netwerk
 Rond kern filamentvrij cytoplasma  perinucleaire halo (gevuld met mitoch en glycogeen)
 Celjuncties tussen hartspiervezels

GEINTERCALEERDE SCHIJVEN p35
Dunnere dwarsstreping = overlapping actine- en myosinefilamenten ≠ dikkere trapvormige strepen =
celjuncties
Geïntercaleerde schijven:
 individuele strepen  tussen 2 opeenvolgende spiervezels
 gans junctioneel complex zowel mechanisch als communicerende juncties
adherens en desmosomen gap junction

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