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Studium generale: Emerging Viruses notes $4.56   Add to cart

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Studium generale: Emerging Viruses notes

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  • January 9, 2022
  • 4
  • 2017/2018
  • Class notes
  • Kevin k. arien
  • Emerging viruses
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Emerging viruses: a perpetual challenge
Kevin K. Arien

Virussen:
- kan alles infecteren (planten, dieren, bacterien,..)
- DNA of RNA met een eiwitmantel en soms enveloppe
- Parasieten
- Replica?e cyclus (zeer complexe cyclus)

Interac?es tussen eiwiEen cel en eiwiEen virus
Spaanse griep: grootste uitbraak tot nu toe gekend
Laatste jaren veel uitbraken, voornamelijk virussen vaak RNA virussen

WHO, pathogen priority list

Aantal belangrijke virussen naar voren die belangrijk zijn voor dringend onderzoek

RNA virussen hebben typisch kleine genomen : tussen 10 en 20 kilobasen (10000 basen)
Hebben oud replica?e systeem  vaak fouten  veel muta?es
Geen controle dus fouten blijven er in ziEen

Doorgaans 1 variant wordt overgedragen en vaak de minst aanwezige (nog niet bekend
waarom)

Zoono7c origin (ZOONOSES)
 de pathogenen die nu opduiken hebben zeer veel varia?e

Meestal overdracht door interach?e met dieren (insectvectoren, krabben, direct contact …)

Voeding in Afrika: Bushmeat  levend vangen van dieren in de bush  direct
bloedcontact,..
VERS vlees = LEVEND vlees

Voeding in Azië: vooral pluimvee, grote cond-centra?es van vogelmarkten (kippen, eenden ,
ganzen,..)  corona, inXuenza

Onderzoek in virologie unit vooral gec. Op Afrika

Human impact on environment

Ontbossing, regenwoud, mens dichter bij dier, de mens dringt binnen in verschillende
ecosystemen
Wereld popula?e enorm: vooral industriele evolu?e hee[ gzorgd voor expon groei
Mensen leven ook op verschillende plaatsen: veel mensen in Azie
Mensen wonen vooral in de steden en er wordt heel erg veel gereisd (vliegtuig)




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