BIOM 500 Quiz 1 LATEST PAPER QUESTIONS WITH ANSWERS 2021/22 100% CORRECT SOLUTIONS

Question 1 2 out of 2 points In which of these conditions would you expect an elevation of p53 expression in normal cells? Selected Answer: All of these  Question 2 0 out of 2 points Which of these TSGs plays an important role in the direct inactivation of a GTPbound Ras oncogene and when it is mutated can result in sporadic sarcomas in affected patients? Selected Answer: [None Given]  Question 3 0 out of 2 points In a patient with a constitutively active receptor tyrosine kinase that increases the activity of PI3K, the administration of a drug that increases PTEN expression will likely inhibit tumorigenesis because; Selected Answer: PTEN competitively inhibits the catalytic subunit of PI3K  Question 4 2 out of 2 points You are evaluating a chemotherapeutic agent whose mode of action involves increasing Cytochrome C release from the mitochondria of treated cells - this drug most likely promotes the activity of this protein; Selected Answer: BA X  Question 5 0 out of 2 points In a patient with Essential thrombocytemia, a mutation in JAK2 - a downstream effector of cytokine receptor, results in a constitutive activation of the pseudokinase domain of the receptor and an inhibition of signaling via this pathway. Selected Answer: Tru e  Question 6 2 out of 2 points Which of these statements is not correct about Cytokine Receptor Signaling? Selected Answer: They are the same as receptor tyrosine kinases  Question 7 2 out of 2 points Mutations in the human homologue of patched is responsible for hereditary nevoid basal cell carcinoma Selected Tru This study source was downloaded by from CourseH on :21:55 GMT -06:00 Answer: e  Question 8 2 out of 2 points The increased efflux of calcium ions from the endoplasmic reticulum is commonly mediated by this downstream signaling molecule; Selected Answer: Inositol triphosphate (I P3)  Question 9 0 out of 2 points The binding of Wnt ligands to LRP5/6 leads to the activation of the destruction complex and translocation of beta-catenin to the nucleus and increased expression of C-Myc. Selected Answer: Tru e  Question 10 0 out of 2 points Which of these is common characteristic of tumor suppressor genes? Selected Answer: All of the above