Classification Prototype Routes, Mechanisms of Indications Contraindications Adverse Effects Pre Drug Nursing
Onset, Action gna Interactions Responsibilities
Duration of ncy
Action
Thyroid Levoyhtroxine PO, IV Identical to Primary and Hypersensitivity Rare at A Can Elderly pts
Hormone (Synthroid, (myxedem thyroid secondary Thyrotoxicosis therapeutic interact go low and go
Replacement Levothyroid, a coma) hormone: hypothyroidism, Severe CV doses with slow
Synthetic T4 etc.) PO: slow increasing or hypothyroid conditions, MI At high doses: grapefruit Measure TSH
oLiothyronine onset metabolic state resulting Adrenal o CV juice serum levels
(cytomel) IV: 6-8 hrs rate from surgical insufficiency (tachycardia, delay to see
oLiotrix DOA: 1-3 (increasing O2 removal of angina) absorption progression
(thyrolar) weeks, consumption, thyroid gland, o CNS of therapy
oThyroid, half life 6- resps, and radiation, or excitability Amount of
desiccated 7 days HR) congenital (tremors, absorption
(armour) Increase rate defect headache, and
of nervousness, bioavailability
metabolism insomnia) varies by
promotes o ↑ metabolism brand stick
growth and can create to 1 brand,
maturation strain on heart don’t switch
by making Lifelong;
body work initially –
harder evaluate
every 2 weeks
Taken
separate from
other meds
for absorption
Taken in
morning
before
breakfast
Check BP, HR,
temp
IF HR > 100
DO NOT GIVE
CNS
excitabilities
check
alertness
, Classification Prototype Routes, Mechanisms Indications Contraindications Adverse Effects Preg Drug Nursing
Onset, of Action nanc Inter Responsibiliti
Duration y actio es
of Action ns
Thyroid Propylthiouracil PO Inhibits the Hyperthyroidism Hypersensitivity Leukopenia 0 blood dyscrasias D Overdose
Hormone (PTU) Onset: first step in Give prior to Caution: bone Glomerulonephritis give
Inhibitor oLugol’s solution weeks thyroid surgery if marrow Arthralgias and joint swelling Synthroid
oMethimazole DOA: hormone someone will depression, liver CNS – HA, vertigo, paresthesias
(Tapazole) 1-1.5 synthesis, have part of disease Goiter at high doses
oPotassium hrs suppresses thyroid removed
Iodide (Thyro- peripheral
Block) conversion
oRadioactive of T4 to T3
iodine
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