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Samenvatting volledige cursus neurologie
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Samenvatting van volledige cursus neurologie + lesnotities + afbeeldingen uit dia's
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2e master geneeskundeNeurologie
W. Vandenberghe
Jana Jacobs
Academiejaar 2021 – 2022
, NEUROLOGIE
Prof. Wim Vandenberghe
Aanbevolen handboeken
• M. Baehr & M. Frotscher. Duus’ Topical Diagnosis in
Neurology. Anatomy, Physiology, Signs, Symptoms. 5th
edition (2012). Uitgeverij Thieme
• H. Blumenfeld. Neuroanatomy through clinical cases. 2nd
edition (2011). Uitgeverij Sinauer
www.neuroexam.com
• S.L. Hauser et al. Harrison’s Neurology in Cinical
Medicine. 4th edition (2017). Uitgeverij McGraw-Hill
1
, Hoofdstuk 1: inleiding
1 Kracht
Wat heb je nodig voor normale kracht?
• Hoger (centraal) motorneuron
• Lager (perifeer) motorneuron
• Skeletspier
- Betekenis in neurologie = je vraagt aan pt om bepaalde spier maximaal aan te spannen, je probeert
als onderzoeker om de spier vd pt te overwinnen
• Normale spier kan je niet overwinnen -> spierkracht is normaal
- Wat nodig voor normale spierkracht?
• 3 cellulaire elementen
• Hoger motorneuron
• Lager motorneuron
• Skeletspier
• Moeten alle 3 in tact zijn
- Verlies van kracht
• Parese = gedeeltelijk krachtsverlies
• Paralyse = volledige verlamming
• Kan door dysfunctie van een van deze drie elementen
2
, 1.1 Hoger motorneuron
4 hersenkwabben
Lateraal zicht Mediaal zicht
Motorische cortex
De cellichamen van de centrale motorneuronen liggen in de cerebrale cortex, vooral in delen van de
frontale kwab onmiddellijk rostraal (anterieur) van de sulcus centralis.
3
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