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Pharmaceutical technology and biopharmacy 1, Nederlandse samenvatting

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Pharmaceutical technology and biopharmacy 1, Nederlandse samenvatting Pharmaceutical technology and biopharmacy 1, Nederlandse samenvatting Pharmaceutical technology and biopharmacy 1, Nederlandse samenvatting Pharmaceutical technology and biopharmacy 1, Nederlandse samenvatting Pharmaceutical ...

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  • February 5, 2022
  • 221
  • 2021/2022
  • Exam (elaborations)
  • Questions & answers
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l
OMo
ARc
PSD|
1
1
629
741




Phar
maceut
icalt
echnol
ogyandbiophar
macy1,
Nederl
andsesamenvat
ting

, l
OMo
ARc
PSD
|1
1
629
741




Ph
arma
ceu
tic
alt
ech
nol
ogya
ndb
iop
har
mac
y1:

Doser
ingsvorme nz i
jnontworpe
nmetb i
ofar
maceuti
schee n
tec
hnologi
s c
h ed oel
s t
el
li
ngend i
eku
nnenwor d
env e
rkreg
e nvi
a
doser
ingsvorme ning eda
c ht
en.Def
ormulebesch
rij
ftdekwali
tat
ie
ve
enkwan t
it
ati
e vec ompositi
evandevor
m, ookdestr
u c
tuurvande
vor
m.
Dedoseri
ngs vormza l1ofme er
deretherapeuti
schesubst
anti
es
beva
ttenme te e
nb epaaldehoevee
lheidhu l
pstof
fen.Hul
pst
offen
kunne
nf unc
t i
o n
a l
i
teit
entoevoegena a
nd ose r
ing
svormenz i
jn
bel
angri
jkomb i
ofarma c
eu t
is
cheent echnol
og i
schedoel
stel
li
ngente
ber
eike
nd i
ev e r
kregenzull
enmoe t
e nword enbij
doseri
ngsvor
m. De
fu
ncti
onali
teitvand edoseri
ngsvor
mi sb epaaldbi
jzowelde
samenstel
l
inga lsstru
c t
uurvandoseri
n g
sv orm.




Bi
ofar
mac
euti
sch
edoe
lst
el
li
nge
n:
re
lea
sepr
ofi
l
e
r
outevantoe
d i
eni
ng(bep
a a
lddes
tru
ctuu
rva
ndos
eri
ngs
vor
mend
e
e
isenwaaraandose
rin
gsvormmoetv
old
oen)
t
arg
e t
ing

Deinn
ovat
iei
nbi
ofa
rmace
uti
sch
edoe
lst
el
li
ngenis
ged
revend
ooron
twi
kke
li
ngeni
nmedi
ci
jnt
her
apie
.
Tec
hnologi
schedoel
st
ell
in
gen(v
aakkwal
i
tei
tens
tab
il
it
ei
ten
mogel
ij
khedenpr
o d
ucti
evansp
ecif
iek
evor
mineenf
ormul
e):
con
tro
lere
nv anp
roces

,s
tab
il
it
ei
t
r
epr
oduce
erb
aar
hei
d

Str
uctuuri
sb e
lan
grij
k,d
es tr
uctu
urvandoser
ing
svormdiev
aakde
func
ti
on al
i
tei
tbepaal
dva ndoser
ing
svor
m. I
nnovat
ie
sin
tec
hnologi
schedoels
tel
li
ngenvandoser
ing
svormenzij
ngedr
eve
n
doorte
c hn
ologi
scheontwik
keli
ngen.

Pr
od u
c t
iemoe tvol
doenaanh ogekwali
tei
tsei
senenv e
rzek
erend a
teen
ef
fect
ief,v
eil
igenb et
rouwbaarme d
ici
jnpr
oductwordtgepr
oduceerdin
eenrepr
o duce
e r
barema n
ier
.Opd ezema ni
erwordtdoser
ings
vorm
gepr
oduc e
erd,kandire
ctaanp at

ntwor d
eningedie
ndofme tbehulp
va
ne ena ppar
aat(bij
v.naal
d).Ennatoedi
eninghopenopthera
p eut
is
ch
ef
fect
. Ef
fectnie
talle
enb epaa
lddoorme di
cij
nsubst
anti
esma arook
doordoseri
ngsvormwa ar
me eme di
ci
jntoegedi
endis.

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297
41




Ther
apeuti
schewe rk
zaamheidvanme dic
ij
nsubst
ant
ieisbepaal
ddoor
:
I
ntr
insi
ekefarmalogi
scheentoxic
ologis
cheeige
nschappenvan
s
ubstanti
e(rec
ep t
orin
ter
acti
e).
Omvange nsnel
he i
dvanlev
erenvans ubst
ant
ieaankantvanact
ie,
b
epaaldebij
:
Deomvan gensne l
hei
dvanvrij
kome nmedici
j
nvando s
e r
ings
vor
m
Depla
atsv anafgi
ft
ev a
nme dic
ij
nsub s
tant
ieui
tdoser
ingsvor
m.
Tr
ansportvanme di
cij
nsub
stanti
evanp l
ekvanadsor
p t
ienaarpl
ekvan
act
ie.
Punt
en1,2
,3zi
jnb
epaal
ddoor
:
Fy
sicoc
hemis
cheeig
ensc
happ
env
anme
dic
ij
nsu
bst
ant
ie
Functi
onel
easpec
tenv a
ndoseri
ngsv
orm( st
ruc
tuu
ren
fy
sicoche
mischeaspe
c t
envandoser
ingsvor
m)
Pl
ekv anvr
ij
la
tenmedici
jnui
tdoser
ings
v or
m
Deroutevanmedi
cij
ntoedi
eni
ngdievoorbepaa
ldmed
ici
j
nisg
eko
zen
Gr
ote
nde
elsb
eïn
vloe
dofb
epa
aldd
oord
ose
rin
gsv
orme
nst
ruc
tuu
r!




Dec onst
a n
tevand i
s s
olut
iep r
oc esend athetmedici
j
no pl
os ti
n
l
ich
a ami sbel
angrij
k.All
eenop gelosteme di
cij
nenkunnend oor
memb raneneninteract
ieheb benme teenreceptor
.Duse e
nme di
ci
jn
moetz i
jnopgel
os tvoorhetwa tkand oen,bi
jnageenéénme di
ci
jn
doetiet
swa nneerhetnoginv astes t
aatis.Eenopl
ossingise e
n
st
abielemolecul
airesprei
dingv anme di
cijni
ne enconti
numa t
ri
x
bev
a tt
endu i
teena nderma t
e r
iaal(wate
rofa nderopl
osmidd el
).
Omd atme di
ci
jn
e nslechtoplosseninv l
oeist
offe
ninli
chaam, isdi
tde

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