In deze samenvatting van FA-MA107 Polyfarmacie zijn de 8 casussen omschreven die in de cursus aanbod gekomen zijn. Bij het schriftelijk tentamen wordt er op een zelfde manier van je gevraagd om een casus uit te werken. Tijdens het mondeling komen deze casussen aanbod. Er wordt een vervolgvraag gevr...
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Leerdoelen ..........................................................................................................................................5
Casus 1; Een vrouw (40 jr) met psychische problematiek .......................................................................6
Casus 2 + 8b; Een man (71 jr.) met atriumfibrilleren ............................................................................ 10
Casus 3; Een vrouw (49 jr.) met DM2 en neuropathische pijn .............................................................. 14
Casus 4; Een man (75 jr.) met Parkinson & trombose .......................................................................... 20
Casus 5; Een vrouw (87 jr.) met Parkinson en verwardheid.................................................................. 26
Casus 6; Een man (63 jr.) met hartfalen na een myocard infarct .......................................................... 32
Casus 7; Een man (70 jr.) met COPD, depressie en beroerte................................................................. 37
Casus 8a; Een vrouw (64 jr.) met de ziekte van Crohn.......................................................................... 44
Jicht (Gout) ....................................................................................................................................... 49
Pathofysiologie van jichtartritis................................................................................................................. 49
Symptomen van jicht................................................................................................................................. 49
Beleid bij jicht ............................................................................................................................................ 49
Acute aanval .......................................................................................................................................... 50
Onderhoudsbehandeling....................................................................................................................... 50
Werkingsmechanismen & veiligheid ......................................................................................................... 51
Prednisolon ........................................................................................................................................... 51
NSAID’s (hoog gedoseerd)..................................................................................................................... 51
Colchicine .............................................................................................................................................. 52
Allopurinol ............................................................................................................................................. 52
Benzbromaron ....................................................................................................................................... 52
Febuxostat ............................................................................................................................................. 53
Inflammatoire darmaandoeningen (IBD) ............................................................................................ 54
Colitis Ulcerosa vs. Ziekte van Crohn ........................................................................................................ 54
Pathogenese en pathofysiologie ............................................................................................................... 55
Collitis Ulcerosa ..................................................................................................................................... 56
De ziekte van Crohn .............................................................................................................................. 57
Medicamenteus beleid.............................................................................................................................. 58
Inductiefase ........................................................................................................................................... 58
Onderhoudsfase .................................................................................................................................... 59
Step up vs top down .............................................................................................................................. 60
Zwangere vrouw met IBD ...................................................................................................................... 61
Chirurgische opties ................................................................................................................................ 61
Personalized medicine .......................................................................................................................... 61
Geneesmiddelen ....................................................................................................................................... 62
Mesalazine(analogen) / aminosalicylaten ............................................................................................. 62
Corticosteroïden .................................................................................................................................... 64
Thiopurines............................................................................................................................................ 64
Methotrexaat ........................................................................................................................................ 65
Ciclosporine ........................................................................................................................................... 65
Tacrolimus ............................................................................................................................................. 65
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