Summary
Sumario Gluconeogenesis
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Proceso de gluconeogenesis en detalle
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gluconeogenesiscar act eristic as generates de la gluconeogenesis
•
proceso destinies is de protein as a part lr de precursor es no glucldlcos
• se real Iza en la mitochondria y en el Clio plasma
• tiene dlstlntos precursor e) In ladies
-
DIRVVATO , tact at 0 , Giller 01 y amino acid 0s
• se da durante ayunol Prolong a dos otros e) era CIO in ten so
• se da en el
nigadoyenelrlñon
• irreversible
VISION global gluconeogenesis
-
• rut a anabolic a const Hulda Dorit reach ones
:( at all 2- a das por en 2- 1m as distant as a
"
-
3 real clones "
bypass la
910101 Isis
1. PIRUVA TO → PEP
2. f- 1,6 BP → FGP
3. 6613 →
glucosa
-
7- react ones invert as a la give 01151s :( at all 2- a das por enzlmas
lgvdles a la
give 01151s
Reach ones bypass ( conversion del PIRUVATO en PEDI
• Esta const it Vida por 4 reach ones ( Cada una se da dos recess
1. Carbo XIIACI On del DIRUVATO -
Irreversible -
MITO Condrla
• so Strato : PIRUVATO
• product 0 : oxalate TATO At Ser Un Proceso anabolic 0
• enzlma :
piruvatocarboxllasa Voy a Tener que Usar Poder
• Balance energetic 0 :
gas to de 1 Atp reductory ATP
2. Reduce 10h del oxalacetato -
mitochondria
• su Strato : OXAIACETATO
• product 0 : MAIA TO
• en -21mA : Mala to desnldrogenasa
• Balance energetic 0 :
gas to 1 NADH t Ht
3. OXIAACIO 'n del MalaTO -
111-0101
• so Strato :
Mala TO
• product 0 : OXAIACETATO
• En -21mA : maid TO deshldrogenasa
• Balance energetic 0 :
creo INADH 1- Ht
, 4. CAVDOXIIACIOÑ t FOSFORIIACIÑH del Oxalate TATO -
( 11-0501
• just rato : oxalate TATO
• product 0 :
FOSFONOIPIVUVATO
• Eh 2- Ima -
-
PEP carboklnasa
• Balance energetic 0 :
gas TO IATP
peace tones bypass -
conversion del lactato en PED
• const Hulda por Tres reach ones ( x2 )
OX1dAllOhdellAlTATO-C1TOSO1oosvsTratOi.1actaTO@prOdUCt0i.p
1.
IRUVA TO
• en 2- Ima : IACTATO dlhldrogenasa
• Balance energetic 0 : Creon NADH 1- Ht
2. carb 0×11011 On del DIRUVATO -
irreversible -
mitochondria
• SU Strato :
plrvvato
•
product 0 : OXAIACETATO
• en -21mA : piruvatocarboxllasa
• Balance energetic 0 :
gas TO de 1 ATP
3. Carb 0×11 Action t FOIFOVIIAC 10h del OXAIACETATO
• svstrato :
oxalate Tato
•
product 0 : FOIFONOIPIRUVATO
• en Zima :
PEP Carboklnasa
• Balance energetic 0 : gas to TOTP
PEP
?
PEP
Ck ( para Pasar de laciato a plrvvato
""
Feta" Gene " Poder " red "Tor " en et
NADA + Ht ( 11-0101 por ende no VA A set
[ NAD
Important e Pasar a MAIATO .
Mahato
Entra a la mitochondria por que la
en 2- IMA PIRUVATO carb 0×11 as a 5010
mania PIP
PEP se encuentro en la mltocondrla
CNAD
NADH + Ht
CK
↳ Ha 90 el PED dentro de la
acetate
^ ^
Mitochondria por que et oxalacetato
pc pc
' no puedesallr de la mitochondria
Plryya gyrator
PIRUVATO
PIRYYATO
NADH Ht
@
t
LDH
/ Alta ,- ONADT
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