100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Summary Chapter 5 summarty (lecture notes + information from the book)(Molecular Biology of the Cell) $3.74
Add to cart

Summary

Summary Chapter 5 summarty (lecture notes + information from the book)(Molecular Biology of the Cell)

 49 views  0 purchase
  • Course
  • Institution
  • Book

Summary of chapter 5 from Alberts. Summary consists of lecture notes and information from the book including pictures.

Preview 2 out of 9  pages

  • No
  • H5
  • March 6, 2022
  • 9
  • 2020/2021
  • Summary
avatar-seller
HC5

E. coli (bacteria) ~4x106 nucleotide pairs
Homo sapiens ~3x109 nucleotide pairs

Mutation rate = 1 nucleotide substitution per 1010 per cell generation
Humans = 100 germ line cell divisions from conception to next germ cell
~70 new mutations in each offspring

Mutation rate limits genome size and the number of essential genes!




errors causing the mutations:
- “normal” polymerization
- proofreading (3’ - 5’)
- mismatch repair

DNA-polymerase:
- katalyseert de reactie van het aanbouwen van nucleotiden
- controleert ook de base-paring -> als fout, zorgt DNA-polymerase dat de nucleotide
wordt ontkoppeld

Two modes (and two catalytic sites) of DNA-polymerase:
- polymerisation
- editing

-> de energetisch gunstige bindingen tussen nucleotiden en de editing functie van DNA-
polymerase zorgen voor hoge precisie bij polymerisatie

primase: zorgt voor initiatie van polymeriseren
- is een RNA polymerase en maakt een RNA primer
- een RNA primer zodat herkent kan worden dat het gaat om RNA en dus nog een
vervangende DNA streng moet krijgen

,

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller julia39. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $3.74. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

53068 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$3.74
  • (0)
Add to cart
Added