Pathogenesis And Clinical Aspects Of Tropical Infe (2087FBDBMW)
Institution
Universiteit Antwerpen (UA)
This document includes the full summary of all lectures of the course Pathogenesis and clinical aspects of tropical infectious diseases of the first Master Biomedical Sciences: Infectious and Tropical diseases. Includes all the information seen in class and on the slides.
Lesson 1: Kevin Ariën ...
pathogenesis and clinical aspects of tropical infectious diseases
Written for
Universiteit Antwerpen (UA)
Biomedische Wetenschappen
Pathogenesis And Clinical Aspects Of Tropical Infe (2087FBDBMW)
All documents for this subject (5)
1
review
By: cedric2016 • 1 year ago
Seller
Follow
Bi0med
Reviews received
Content preview
Pathogenesis and clinical aspects of
tropical infectious diseases
The written exam counts for 75% (15/20). The exam consists of a 10-15 open questions that cover most
chapters. The questions assess rather general knowledge. Some questions also assess if the student is
able to see relationships between different chapters. 25% (5/20) of the total quotation is dedicated to
the seminar series, where the quality of the presentation and discussion during the seminar is marked.
1. VIRAL ZOONOTIC DISEASES WITH GLOBAL PUBLIC HEALTH IMPACT 14/02
3 examples of zoonotic epidemic viruses:
1. HIV: Originates from Simian IV (SIV)
2. Ebola virus: reservoir is not known yet. First reported in 1976
3. Dengue: mosquito born disease. First described in 1780, reported as Dengue in 1960’s
HUMAN IMMUNODEFICIENCY VIRUS (HIV)
THE ORIGINS OF HIV
For finding the origins of HIV, they collected faeces of non-human primates in tropical areas to look
for Ab against HIV-related viruses. On the Ab-positive specimens they looked for viral RNA with PCR.
Using mtDNA sequencing they determined from which animal the faeces were.
A PHYLOGENETIC TREE was build containing SIV and HIV viruses. Many monkeys
and non-human primates have their own specific SIV. HIV viruses such as HIV-1
M caused the worldwide problem of HIV and closely relate to SIV viruses.
- HIV-1 group M is closely related to SIV in chimpanzees
- HIV-1 group P and HIV-1 group O are related to SIV in gorillas
Based on the phylogenetic trees and where the samples were collected, they geographically localised
the initial jump from SIV to humans. They traced in back to the southern part of Cameroon and Gabon
(central – west Africa). The ORIGINS OF HIV-2 are traced back to West-Africa. Also here different
subtypes of HIV-2 have jumped into humans and have been located to specific regions where Sootey
Mangabey monkeys that were infected by specific SIV viruses could be located. Infection can jump to
humans during CAPTURING MONKEYS / PREPARATION OF BUSH MEAT : direct blood-blood contact possible.
1
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Bi0med. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $16.87. You're not tied to anything after your purchase.
