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Treatment of Hypothyroidism with Levothyroxine Chamberlain College of Nursing NR 293 – Pharmacology Hypothyroidism is a disease in which there is a problem with the production of the thyroid hormone. Patients with hypothyroidism are typically fatigued, have mild to moderate weight gain, muscle we...

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  • March 18, 2022
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RUNNING HEAD: LEVOTHYROXINE FOR HYPOTHYROIDISM Page |1




Treatment of Hypothyroidism with Levothyroxine

Chamberlain College of Nursing

NR 293 – Pharmacology




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, LEVOTHYROXINE FOR HYPOTHYROIDISM Page |2


Hypothyroidism is a disease in which there is a problem with the production of the

thyroid hormone. Patients with hypothyroidism are typically fatigued, have mild to moderate

weight gain, muscle weakness, trouble with concentration, and are often depressed (Chiovato,

Magi, & Carle, 2019). In order to treat hypothyroidism, medication needs to be prescribed that

mimics the thyroid hormone. A popular medication for patients with hypothyroidism is

levothyroxine. Levothyroxine is a synthetic version of the body's natural thyroxine (T4) hormone

and is indicated to treat primary, secondary, and tertiary hypothyroidism (Eghtedari & Correa,

2020).

Levothyroxine is available in an oral form, which includes capsule, tablet, and solution.

This medication can also be given intravenously and is only used to treat myxedema coma or

severe hypothyroidism (Eghtedari & Correa, 2020). While the patient is on levothyroxine, their

TSH levels need to be checked. TSH levels look at free T3 and T4, which helps identify if thyroid

levels are within normal limits, are too high, or too low (Eghtedari & Correa, 2020). To maintain

a healthy thyroid hormone level, these labs need to be checked periodically for the duration of

treatment. Treatment is lifelong, as there is no cure for hypothyroidism.

Thyroid medications are contraindicated in those who have uncorrected adrenal

insufficiency, patients with acute myocardial infarction, acute myocarditis, and people with

thyrotoxicosis or hyperthyroidism (Eghtedari & Correa, 2020). There are some adverse effects of

levothyroxine, including anxiety, tachycardia, irritability, reduced fertility, decreased bone

mineral density, nausea, vomiting, and myocardial infarction (Eghtedari & Correa, 2020). The

nurse administering the medication should keep in mind that this medication is to be given on

an empty stomach; therefore, absorption increases. Before the nurse administers the



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