Summary
Samenvatting biologische database leerjaar 2
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Een samenvatting van alle lessen gevolgd op Avans Hogeschool voor het vak biologische database incl. de powerpoints en extra aantekeningen
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,Cheyenne van Kraaij, P2.2, BMO, Biologische database2022
Biologische
database
BMO PERIODE 2.2
CHEYENNE VAN KRAAIJ
AVANS HOGESCHOOL | Breda
1
, Cheyenne van Kraaij, P2.2, BMO, Biologische database
Leerdoelen
Les 1
Weet wat NCBI betekend
Weet welke databases er zijn in NCBI
Ken de types van BLAST
Ken de BLAST parameters
Weet wat de genen AMELX en AMELY betekenen
Wat kun je verwachten bij een AMELX en AMELY PCR experiment
Weet hoe je een primer(set) moet plaatsen in een gene sequence
Weet hoe je de verwachte size van je PCR product kan berekenen
Les 2
Weet hoe je de BLAST output moet evalueren
o E-value
o Bit-score
o Identy/similarity percentage
Weet de statistics van E-value calculation while considering DNA
Begrijp de alignment penalty
Begrijp de amino acid substitution table
Wat is een local aligment
Wat is een global aligment
Weet welke aligment methode is gebruikt in BLAST
Wat is pairwise alignment
Wat is een multiple sequence alignment
Les 3
Herken verschillende typen nodes in een phylogenetic tree
Interpeteer branch lengtes m.b.t. de evolutionary tijd
Weet wat bootstrapping is
Weet wat support value is
Rotate branches en interpreteer radial en polar trees
Distinguish orhologous en pralogous genen in een boom
Leg uit hoe gen functions evolueren
Transfer functional annotations between genes
Reconcilate gene trees en species trees
2
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