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Clayton’s Basic Pharmacology for Nurses 19th Edition Test Bank - All Chapters
Test Bank For Clayton's Basic Pharmacology for Nurses 19th Edition All- Chapters 1-48 |Latest Test Bank With Complete Solution Guide.
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NURS 6521 week 6_Complete Answered Solution
guide; Fall 2022.
Chapter 11, "Basic Principles of Neuropharmacology" (pp. 67-71) Chapter 12, "Physiology of the
Peripheral Nervous System" (pp. 72-81) Chapter 12, "Muscarinic Agonists and Cholinesterase Inhibitors"
(pp. 82-89) Chapter 14, "Muscarinic Antagonists" (pp. 90-98) Chapter 15, "Adrenergic Agonists" (pp. 99-
107) Chapter 16, "Adrenergic Antagonists" (pp. 108-119) Chapter 17, "Indirect-Acting Antiadrenergic
Agents" (pp. 120-124) Chapter 18, "Introduction to Central Nervous System Pharmacology" (pp. 125-
12…
_______ can be defined as the study of drugs that later processes controlled by the
nerovus sytem
✓- neuropharmacology
two basic steps of of neuropharmacologic drugs....
✓- axonal conductionand synaptic conduciton
two influence a process under neuronal control, a drug can alter one of two basic
neuronal activities...
1)
2)
✓- 1) axonal conduction
2) synaptic transmission
is axonal coonduction very selective?
✓- no
drugs that alter synaptic transmission can produce effects that are _______( highly or
minimally?) selective?
✓- highly
the ability of a neuron to influence the behavior of another cell depends untilamtely on
what?
✓- the ability of the neuron to alter receptor activity on the target cell
T or F. the effect of a drug on a neuronally regulated process is dependent on the ability
of that drug to directly or indirectly influence receptor activity on target cells.
✓- TRUE very important
for synaptic transmission to take Place alce, molecules of transmitter must be present in
the ________ _______?
✓- nerve terminal
what is the first step of transmission for neuro drugs?
,✓- transmitter synthesis
what is the second step of transmitter storage?
✓- transmitter storage
what is step 3 of synaptic transmission?
✓- transmitter release
transmitter release is triggered by the arrival of an ______ _____-
✓- action potential
after release, transmitter molecules _______ across the synaptic gap and then undergo
reversible binding to receptors ton the postsynaptic cell
✓- diffuse
the 5th step in transmitter release is when the transmission is terminated by dissociation
of transmitter from its receptor, followed by removal of a free transmitter from the
synaptic gap ✓-
transmitter can be removed fomr the synaptic gap by three processes
1
2
3
✓- 1 reuptake
2 enzymatic degradation
3 diffusion
in synapses where the transmitter is cleared by enzymatic degradation, the synapse
contains large quantities of transmitter-inactivating _______
- ✓- enzymes
all neuropharmacologic agents, produce their effects by directly or indirectly altering
__________ _________.
✓- receptor activity
T or F receptor activtoin can make a process only go faster?
✓- FALSE it can mek it go faster or slower
there are 3 different effects that drugs are known to have on. transmitter synthesis
✓- 1 increase transmitter synthesis
2 decrease transmitter synthesis
3 cause the synthesis to transmitter molecules that are more effective than the natural
transmitter itself
, a drug that increases transmitter synthesis will cause receptor activation to ( INCREASE
OR DECReASE)?
✓- increase
release of "super" transmitters will cause recepto ractivaiton to ________
✓- increase
drugs that interefere with transmitter storagfe will cause the receptor activation to (
INCREASE OR DECREASE)?
✓- decrease
drugs either promote or inhibit transmitter release, amphetamines are examples of
drugs that represent
✓- promoting transmitter relsease
drugs that omhibit relsease will ______ receptor activation
✓- reduce
drugs that directly activate receptors are called ______
✓- agonists
drugs that prevent receptor activation are called ______
✓- antagonists
do morphine, insulin and epinephrine bind directly to the receptor and cause activation?
✓- yes
drugs like naloxone, antihistamines and metoprolol bind directly to receptors and
prevent activation, True or false?
✓- true
Benzodiazepines are an excellent example of a drug that binds to receptors and
________ the actions of a natural transmitter.
✓- enhance
T or F. Drugs can interfere with the termination of transmitter action by two
mechanisms:
1 blockade of transmitter reuptake
2inhibtion of transmitter degradation
✓- true
what is one of the most desirable qualities a drug can have?
✓- selectivity
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