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Test Bank for Janeway’s Immunobiology, 9th Edition By Kenneth Murphy, Casey Weaver
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TEST BANK FOR JANEWAY’SIMMUNOBIOLOGY, 9TH EDITION BY
KENNETH MURPHY, CASEY WEAVER
, JANEWAY'S IMMUNOBIOLOGY, 9TH EDITION
CHAPTER 2: INNATE IMMUNITY: THE FIRST LINES OF DEFENSE
Anatomic barriers and initial chemical defenses
2-1 Infectious diseases are caused by diverse living agents that replicate in their hosts
2.1 Multiple choice: Antibodies, complement proteins, and phagocytic cells provide
effective protection against all of the following types of infections in Figure Q2.1, except:
Figure Q2.1
2.2 Multiple choice: Pathogenic infections induce damage to the host by a variety of
mechanisms. While many mechanisms are direct effects of the pathogen, some
damaging mechanisms result from the immune response to the infection, as illustrated in
Figure Q2.2. Examples of damage caused by the host immune response are:
Page 1 of 19
, Figure Q2.2
2.3 True/False: Mucosal surfaces and external epithelia are major routes of pathogenic
infection. Mucosal surfaces are found in tissues such as the gastrointestinal tract, the
reproductive tract and the mouth and respiratory tract. While the mouth and respiratory
tract are routes of virus but not bacterial infections, the gastrointestinal tract is the route
for bacterial but not virus infections.
2-2 Epithelial surfaces of the body provide the first barrier against infection
2.4 Multiple choice: Epithelial surfaces provide the first line of defense against infection by
the use of several types of mechanisms. One of the chemical mechanisms used by
epithelia is:
A. Joining of epithelial cells by tight junctions
B. Secretion of antimicrobial peptides by epithelial cells
Page 2 of 19
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