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NR 292 STUDY GUIDE EXAM II WITH ANSWERS.

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NR 292 STUDY GUIDE EXAM II WITH ANSWERS.

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  • May 2, 2022
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  • 2021/2022
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Study Guide
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NR 292 STUDY GUIDE EXAM II WITH
ANSWERS

50 Questions – Multiple Choice, Select All That Apply, Multiple Sequence


Chapter 30: Pituitary Drugs

 Therapy is lifelong
 Examples of drugs
o Anterior: Cosyntropin, Somatropin, Somatrem, Octreotide
 Cosyntropin: synthetic cortisol – used in diagnosis of adrenal
insufficiency, stimulates release of cortisol from adrenal cortex, cortisol
has anti-inflammatory effect and renal retention of sodium
 Somatropin and Somatrem: mimic Growth Hormone, effects on skeletal
and cellular growth (stimulate skeletal growth in pts with deficient GH
such as hypopituitary and dwarfism, replacement for adults with
pituitary disease
 Octreotide: antagonizes the effects of GH by inhibiting release, decrease
plasma concentrations of vasoactive intestinal polypeptide (reduces
severe diarrhea associated with VIP tumors), also used to treat
esophageal varices
o Posterior: Vasopressin, Desmopressin, Oxytocin
 Desmopressin: increases factor VIII – useful for some bleeding
disorders, nocturnal enuresis, diabetes insipidus
 Vasopressin: potent vasoconstrictor in large doses – hypotensive crisis,
esophageal varices, diabetes insipidus
 Oxytocin: mimics uterine contractions by stimulating uterine smooth
muscle, used for induction of labor and postpartum bleeding,
vasopressor and antidiuretic effects
 Got to Know
o Octreotide
 Suppresses secretion of GH, insulin, and glucagon
 Used for diarrhea management for pts with AIDS
 Can cause hypotension r/t reabsorption of fluids/electrolytes
o Vasopressin & Desmopressin
 Avoid used of alcohol as it decreases ADH hormone effect
 Monitor for s/s of hypervolemia

, Study Guide
2

o Somatropin
 Maintain growth chart for children being treated for primary dwarfism




Chapter 31: Thyroid and Antithyroid Drugs

 Thyroid Replacement Drugs
o Natural – dessicated (dried up animal T3&T4): not as predictable and not as
commonly used
 Hyperthyroid Drugs: Methimazole, Propylthiouracil
o Methimazole blocks iodine from getting to the thyroid so less T3 and T4 is made
 Got to Know
o Levothyroxine
 TSH is high when thyroid function is low
 Full effects may not be felt for up to 3-4 weeks
 Once daily dosing due to long half life
 Dose in AM due to insomnia (same time each day)
 Take on empty stomach with full glass of water
 ^metabolism = ^HR = ^O2 demand = ^ risk for cardiac issues
 ^ blood glucose levels and interferes with: insulin, oral antidiabetics,
digoxin, phenytoin, phenobarbital (highly protein bound meds)
o Methiamazole & Propylthiouracil (PTU)
 May cause drowsiness
 Can cause liver toxicity – monitor LFTs
 May cause bone marrow suppression
 Avoid foods containing Iodine (seafood, soy sauce, tofu, and iodized
salt)
o Levothyroxine is measured in mcg and Dessicated is measured in mg

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