Kwantitatieve Genetica En Pathogenetica (G000839A)
Institution
Universiteit Gent (UGent)
Inhoud lesslides + lesnotities. Vaak aangevuld met zaken uit de cursus. Ik haalde 18/20, jij kan het ook! Sinds dit jaar is er een nieuwe professor / leerstof. Deze samenvatting is dus helemaal up to date!
Kwantitatieve Genetica En Pathogenetica (G000839A)
All documents for this subject (2)
2
reviews
By: inesmievis • 1 year ago
By: cheyenneyseboodt1 • 1 year ago
Seller
Follow
tineh
Reviews received
Content preview
PATHOGENETICA
Prof. Bart Broeckx
1E MASTER DIERGENEESKUNDE
,1
,Inhoudstafel pathogenetica
H1) Algemene aspecten pathogenetica en populatiegenetica……………………………………………. 10
A. NIVEAU DNA ……………………………………………………………………………………………………………………………….. 10
Take home message
Terminologie
Hoe gaan we varianten classificeren?
Hoe ontstaan varianten? Spontane mutagenese
De link met fenotypes
Complicerende factoren
B. NIVEAU DIER …………………………………………………………………………………………………………………………………13
Take home message:
Kenmerk erfelijk of niet?
Patroonherkenning stambomen
.
Beschikbaarheid en selectie DNA-testen
Interpretatie DNA-testen
C. NIVEAU POPULATIE …………………………………………………………………………………………………………………… 14
Take home message:
Definitie populatie
Varianten op populatieniveau: link genotype - allelfrequentie
Genotypefrequentie
Allelfrequentie
Wet Hardy-Weinberg equilibrium
Factoren die allelfrequentie beïnvloeden
0) Panmixie
1) Mutaties
2) Migratie
3) Selectie
Soorten selectie
Effect van natuurlijke selectie op fenotype.
Algemene selectiemodel
Verschillende selectietypes
2
, 4) Genetische drift
5) Selectie – mutatie evenwicht
6) Inteelt en verwantschap
Inteelt
Begrippen
Inteeltcoëfficiënt F
Berekening van F voor individuen.
Berekening van F voor populaties.
Inteelt op populatieniveau
De effectieve populatiegrootte Ne
Berekening van F voor populaties
Inteeltdepressie
Daling heterogeniciteit populatie door inteelt
Verwantschap
Wat is verwantschap
Directe verwantschap
Collaterale verwantschap
3
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller tineh. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $7.05. You're not tied to anything after your purchase.