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Samenvatting Pathogenetica

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Inhoud lesslides + lesnotities. Vaak aangevuld met zaken uit de cursus. Ik haalde 18/20, jij kan het ook! Sinds dit jaar is er een nieuwe professor / leerstof. Deze samenvatting is dus helemaal up to date!

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  • May 17, 2022
  • 71
  • 2021/2022
  • Summary

2  reviews

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By: inesmievis • 1 year ago

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By: cheyenneyseboodt1 • 1 year ago

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PATHOGENETICA
Prof. Bart Broeckx




1E MASTER DIERGENEESKUNDE

,1

,Inhoudstafel pathogenetica
H1) Algemene aspecten pathogenetica en populatiegenetica……………………………………………. 10

A. NIVEAU DNA ……………………………………………………………………………………………………………………………….. 10
Take home message
Terminologie
Hoe gaan we varianten classificeren?
Hoe ontstaan varianten? Spontane mutagenese
De link met fenotypes
Complicerende factoren


B. NIVEAU DIER …………………………………………………………………………………………………………………………………13
Take home message:
Kenmerk erfelijk of niet?
Patroonherkenning stambomen
.


Beschikbaarheid en selectie DNA-testen
Interpretatie DNA-testen


C. NIVEAU POPULATIE …………………………………………………………………………………………………………………… 14
Take home message:
Definitie populatie
Varianten op populatieniveau: link genotype - allelfrequentie
Genotypefrequentie
Allelfrequentie
Wet Hardy-Weinberg equilibrium
Factoren die allelfrequentie beïnvloeden
0) Panmixie
1) Mutaties
2) Migratie
3) Selectie
Soorten selectie
Effect van natuurlijke selectie op fenotype.
Algemene selectiemodel
Verschillende selectietypes


2

, 4) Genetische drift
5) Selectie – mutatie evenwicht
6) Inteelt en verwantschap
Inteelt
Begrippen
Inteeltcoëfficiënt F
Berekening van F voor individuen.
Berekening van F voor populaties.
Inteelt op populatieniveau
De effectieve populatiegrootte Ne
Berekening van F voor populaties
Inteeltdepressie
Daling heterogeniciteit populatie door inteelt


Verwantschap
Wat is verwantschap
Directe verwantschap
Collaterale verwantschap




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