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Samenvatting Schematische voorstelling Farmacologie $11.39   Add to cart

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Samenvatting Schematische voorstelling Farmacologie

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Schematische voorstelling van geneesmiddelen met agonistische/ anatgonistische werking op het alfa-adrenerg, beta-adrenerg, cholinerg, dopaminerg, serotinerg systeem. Schematische voorstelling van risicopopulaties (kinderen, zwangeren, oude populatie, patiënten met NI, patiënten met LI) en ...

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  • May 30, 2022
  • 1
  • 2020/2021
  • Summary
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Zuivere, milde agonisten
Codeïne Tramadol Tilidine Bupernorfine
(gemengde
agonist-anta)
Indicatie Hoestwerend
Milde diarree
Hevige acute/
chronische pijn
Milde pijn Substitutietherapie

Combinatie Paracetamol Paracetamol
NSAIDs
Altijd met naloxon



Farmacodyna CYP2D6 u-agonist + reuptake
inhibitor (NA & 5HT)
Biotransfer: nortilidine
& bisnortilidine
Heel groot first pass
effect
miek CYP2D6  parentaal,
intradermaal,
sublinguaal,
dransdermaal
Hoge affiniteit U, K en
lamda
 partiele u agonist
Neveneffecte Nausea en braken bij
start
!!! combo andere
n Vertigo, sedatie, droge
opioïden
mond
!!! moeilijke dosering

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