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NR 565 Week 3 Discussion: ANS Case Study/ Responses (TOP RATED)

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NR 565 Week 3 Discussion: ANS Case Study/ Responses Responses Kaycee Parrillo Hello Kaycee. Thanks for your post. I agree with your treatment goals of discontinuing clonidine since the patient p resents with adverse side effects. As reported by the patient, the tremors have since increased since sh...

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NR 565 Week 3 Discussion: ANS Case Study/ Responses

Responses

Kaycee Parrillo

Hello Kaycee. Thanks for your post. I agree with your treatment goals of discontinuing

clonidine since the patient presents with adverse side effects. As reported by the patient, the

tremors have since increased since she was placed on clonidine. However, you should have a

plan to gradually discontinue the medication by tapering before eventually introducing

propranolol. Considering the side effects on both drugs on patient with tremor, research shows

that propranolol has been effective in reducing tremors with limited side effects as opposed to

clonidine (Hall et al., 2016). I could not locate the article you used in this post, but found a

similar study investigating the effect of clonidine in patients with essential tremor in double-

blind placebo-controlled design, clonidine therapy was ineffective in treating essential tremor

(Koller et al., 1986). It could be argued that the introduction of clonidine did not yield any

effects on the patient. Therefore, a replacement would be the best option for Margaret.

References:

Hall, K., Kossowsky, J., Oberlander, T., Kaptchuk, T., Saul, J., & Wyller, V. et al. (2016).

Genetic Variation in Catechol-O-Methyltransferase Modifies Effects of Clonidine

Treatment in Chronic Fatigue Syndrome. The Pharmacogenomics Journal, 16(5), 454-

460. DOI: 10.1038/tpj.2016.53

Koller, W., Herbster, G., & Cone, S. (1986). Clonidine in the treatment of essential tremor.

Movement Disorders, 1(4), 235–237. https://doi.org/10.1002/mds.870010403




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