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Lecture 1 notes hand written
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131056008 based Medicine and21 Evidence
Diagnostics
-
-
"
Evidence based medicine is the conscientious ,
explicit ,
and
evidence
judicious use of current best in
making decisions
"
about the care of individual patients .
> The randomised
strongest evidence comes from meta -
analysis ,
controlled clinical trials and systematic reviews .
> EBM evolved evidence based medical :
has also into -
practice
developing guidelines and policies for groups of patients or
populations .
Coursework -
two pieces 50% total
,
> Week 5 : Online MCQ on
epidemiology ( 20% )
> Week 8 :
drug information leaflet for Dr and patient (30%)
coursework 2
* Does to inc side effects
not require
.
,The exam ( 50%3
, L1 History and Rationale
History of evidence -
based medicine
> >
Historically
( decision
Doctor knows best
approach
-
made
,
by physicians based on clinical
judgement / practicing the ar t
of medicine .
. . .
Symptom 8 Symptom Patterns Among Gulf War Registry Veterans
Personalised Medicine versus era of Us Trial and Error
A history of cancer chemotherapy
> The use of chemotherapy to treat cancer
began at the star t
of the 20th
century with attempts to nar row the universe
of chemicals that
might affect the disease by developing methods
to chemicals rodents
screen
using transplant able tumors in .
related
programs , and
> It was , however , four world war II -
the effects
evolved them provided establish
of drugs that from > that the impetus to
1955 the Cancer
in the national
drug development effort known as
Chemotherapy National Service centre .
3- principles of Serendip : Insight ,
chance and discovery in
qualitative research
,
what ?
changed
> Late 1960s onwards
questions asued which challenged if the
Doctor does
actually know best .
. .
( 1967) clinical
Feinstein judgement
•
-
Clinical reasoning and biases that affect it
°
Cocharane (197-2) Effectiveness and Efficiency :
Random Reflections
on health services
-
Lack clinical data
of to support practice
•
Eddy ( 1980s ) e.
g. Variations in
Physician practice : The role of uncertainty
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