Contra-
Indicatie Werking Dosering Kinetiek Bijwerkingen Interacties
indicaties
Bactericide
Remt bacteriële
Tuberculose RNA-polymerase, Altijd in Roodverkleuring
Lepra waardoor remming combinatie met Toediening oraal of lichaamsvloeistoffen Antipsychotica
Rifampicine
Brucellose eiwitsynthese andere AB op i.v. Huidreacties VKA
Profylaxe meningokokkose Effect is afhankelijk resistentie te Bij orale toediening Gastro-intestinale Digoxine
Adjuvans bij infecties van van de voorkomen volledige absorptie bijwerkingen Antimycotica
protheses of ander vreemd piekconcentratie (hoe Geen aanpassing Excretie van gal en Flu-like syndroom OAC niet meer
lichaam materiaal met hoger, hoe beter) bij verminderde urine Asymptomatische werkzaam
gram+ bacteriën Dood de snel- en NF stijging leverenzymen
langzaam delende
tuberkelbacillen
CYP3A4 substraat
Stimuleert zijn eigen
omzetting door Opnieuw
Remt inductie van epileptische insulten
Carbamazepine
Ontlading van CYP3A4 (auto- Misselijkheid Rifampicine
Epilepsie HIV-remmers
neuronen inductie) Duizeligheid HLA-
Trigeminusneuralgie
Synaptische impulsen De halfwaardetijd Hyponatriëmie B*1502
Centrale diabetes insipidus
Catecholamine- zal dus in de loop SJS allel Verder:
(ook bij kinderen)
omzetting van de behandeling TEN Hormonale
Glutamaat vrijgifte afnemen anticonceptie
Induceert ook VKA
CYP2A1 en
CYP2C9
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