What are compounds produced by one microbe that adversely affect other microbes? Correct Ans:- antibiotics
What is the term for an antibiotic that is effective against many species, such as both gram - and +? Correct Ans:- broad spectrum
- can attack structures common to all bacterial cells...
What are compounds produced by one microbe that adversely affect other
microbes? Correct Ans:- antibiotics
What is the term for an antibiotic that is effective against many species, such
as both gram - and +? Correct Ans:- broad spectrum
- can attack structures common to all bacterial cells
What is the term for an antibiotic that is only effective against a certain
species, such as out the outer membrane of gram - cells? Correct Ans:-
narrow spectrum
What is the term for antibiotics that kill target organisms? Correct Ans:-
bactericidal
What is the term for antibiotics that prevent the growth of the organism but
do not kill? Correct Ans:- bacteriostatic
What is the scientific contribution of Duchesne? Correct Ans:- proposed that
bacteria and molds engage in a perpetual battle for survival
What is the scientific contribution of fleming? Correct Ans:- rediscovered
penicillin
What is the scientific contribution of Florey? Correct Ans:- purified penicillin
with Chain
What is the scientific contribution of chain? Correct Ans:- purified penicillin
with Florey
What is the scientific contribution of Domagk? Correct Ans:- - discovered
sulfa drugs (prontosil dye)
- inactive until the body converts it to an active agent
What is the scientific contribution of Waksman? Correct Ans:- discovered
streptomycin, an antibiotic produced by actinomycete bacterium found in
soil
What are the 2 criteria for an effective antibiotic? Correct Ans:- 1. antibiotic
must affect the target organism
2. it must not affect humans
, What are the differences in MIC and MBC and the technique for finding each?
Correct Ans:- - MIC is the lowest concentration that prevents growth
- to test for MIC, dilute the antibiotic and see which concentration has no
visible growth. you can also use a strip test
- then, plate each tube with no visible growth. see if colonies form: no
colonies = MBC (or MLC)
explain the procedure and information obtained for a Kirby-Bauer Disk assay
Correct Ans:- - tests strain sensitivity to multiple antibiotics
- you have round filter paper discs soaked in antibiotics. place them on agar
with a bacterial lawn streak and see if there is a zone of inhibition
what is the cellular target for PCN? Correct Ans:- cell wall
what is the cellular target for Vancomycin? Correct Ans:- cell wall
what is the cellular target for Polymyxin? Correct Ans:- cell membrane
what is the cellular target for Gramicidin? Correct Ans:- cell membrane
what is the cellular target for Amingoglycosides? Correct Ans:- protein
synthesis
what is the cellular target for Tetracycline? Correct Ans:- protein synthesis
what is the cellular target for Rifamycin B? Correct Ans:- RNA synthesis
what is the cellular target for actinomycin D? Correct Ans:- RNA synthesis
what is the cellular target for sulfa drugs? Correct Ans:- DNA synthesis
what is the cellular target for quinolones? Correct Ans:- DNA synthesis
what are the 4 key steps of peptidoglycan synthesis and how do certain
antibiotics disrupt the process? Correct Ans:- 1. precursors are made in
cytoplasm
2. the precursors are polymerized to the existing cell wall structure by
transglycosylases
3. the peptide side chains are cross-linked by transpeptidases
what is the mechanism of action for beta lactam antibiotics and what
antibiotics are classified as beta lactams? Correct Ans:- - Beta lactams are
penicillins and cephalosporins
- inhibit cell wall synthesis
- the beta-lactam ring chemically resembles the D-Ala-D-Ala piece of
peptidoglycan
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller LeCrae. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $14.49. You're not tied to anything after your purchase.
