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microbiologie: samenvatting (boek + les) hfst 7 - inleiding

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microbiologie - Van Eldere samenvatting (boek + les) hfst 7 - legionella pneumophila

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  • June 17, 2022
  • 3
  • 2021/2022
  • Summary
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RESPIRATOIRE INFECTIES
1. ALGEMEEN

 Respiratoire infecties = veruit belangrijkste
o Voorkomen
 70% vd infecties waarvoor een arts geraadpleegd w zijn respiratoire infecties
o Ernst

2. AFWEERMECHANISMEN LUCHTWEGEN




2.1 NASOFARYNX

 Commensale flora
o “bezetten van alle parkeerplaatsen”
 Pathogene bacteren bezitten middelen om deze commensale flore uit te roeien
 Secreties
o Lysosyme
 Een enzyme dat de celwand vd bacterie afbreekt
o sIgA
 gaat de bacterie binden & ze daardoor gevoeliger maken voor fagocytose
o lactoferine
 Een enzyme dat een chelator is. Het gaat ijzer gaan binden en dus zorgen voor een lage concentratie
ijzer id slijmvliezen terwijl bacterien ijzer nodig hebben om te kunnen groeien
o Fagocyten
 Gaan de bacterien fagocyteren

2.2 TRACHEA & BRONCHI

 Mucociliaire lift
o In de slijmvliezen zijn er mucossecreterende cellen (productie mucus) en ciliaire cellen (verplaatsing mucus).
o Bacterien geraken zo getrapt in de mucuslaag & worden terug naar onze keel beborsteld
 sIgA

opm: trachea & bronchi bevatten geen commencale flora

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