NEPHROTIC SYNDROME
,Definition:
The nephrotic syndrome is a renal
disorder with many possible causes
characterized by massive proteinuria,
hypoalbuminemia, hyperlipidemia,
lipiduria, and generalized edema.
, • Pathogenesis: the renal diseases
associated with the nephrotic
syndrome produce an increase in
glomerular permeability for large
molecules such as proteins. This
may result from generalized
basement membrane injury or loss
of basement membrane -
associated polyanions
,Definition:
The nephrotic syndrome is a renal
disorder with many possible causes
characterized by massive proteinuria,
hypoalbuminemia, hyperlipidemia,
lipiduria, and generalized edema.
, • Pathogenesis: the renal diseases
associated with the nephrotic
syndrome produce an increase in
glomerular permeability for large
molecules such as proteins. This
may result from generalized
basement membrane injury or loss
of basement membrane -
associated polyanions
