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Samenvatting Het Immuunsysteem
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Samenvatting over het immuunsysteem
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ContentsInnate immunity.....................................................................................................................................2
Ontstekingsreactie (korte versie, enzymen)...........................................................................................2
Sensorsystemen (kort overzicht)............................................................................................................3
Het complement systeem.......................................................................................................................3
, Innate immunity
- Is vanaf de geboorte actief.
- fysieke barrières (huid en slijmvliezen
- Sensorsystemen (PRR en complement)
Effectoren PRR -> ontstekingsreactie en inferonen
Effectoren complement -> ontstekingsreactie, inferonen, opsonisatie en
Membrane Attack Complexes (MAC).
PRR= Patroonherkenningsreceptoren
Ontstekingsreactie (korte versie, enzymen)
Lysosym: enzym dat peptidoglycaan afbreekt. Te vinden in slijm, traanvocht en speeksel,
maar ook o.a. in fagocyterende cellen bloed.
Peroxidase: enzym dat antimicrobiotische compounds, mbv H2O2.
Microorganisme die het enzym katalase gebruiken zijn minder vatbaar voor dit enzym
doordat ze dit makkelijk kunnen omzetten in H2O en O2.
Peroxidase is te vinden in moedermelk, slijm, lichaamsweefsels en fagocyten.
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