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Summary Gastrointestinal tract Most common disorders

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In this document you will find a revision including all the common disorders of the GI tract, diagnosis, signs and symptoms, lab findings, treatment options

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  • July 30, 2022
  • 62
  • 2021/2022
  • Summary
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Available practice questions

Flashcards 36 Flashcards
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Some examples from this set of practice questions

1.

What is the most common extrahepatic manifestation of celiac disease involving the skin?

Answer: Dermatitis herpetiformis

2.

What part is most commonly affected in SMALL intestine obstruction?

Answer: Ileus

3.

what is the most common part affected in LARGE bowel obstruction?

Answer: sigmoid colon

4.

Why do you avoid enemas when diagnosing a patient with suspected intestinal obstruction?

Answer: distortion of XRAY image

5.

What is the most common cause of intestinal ischemia? 1)non-occlusive disease 2)arterial thrombotic disease 3)arterial embolism 4)venous thrombotic disease

Answer: 3-arterial embolism

6.

What is the most common cause of intestinal ischemia in a YOUNG patient? 1)venous thrombotic disease 2)arterial embolism 3)non-occlusive disease 3)arterial thrombotic disease

Answer: 1-venous thrombotic disease

7.

What symptom is expected in a patient with pancreatic cancer in the HEAD of the pancreas?

Answer: jaundice

8.

what sign is expected in a patient with pancreatic cancer in the BODY or TAIL of the pancreas?

Answer: pain and weight loss

9.

What marker can be used to diagnose pancreatic cancer?

Answer: CA 19-9

10.

What marker can be used to diagnose colorectal carcinoma?

Answer: CEA

CELIAC DISEASE
Symptoms:
 Abdominal bloating
 Diarrhea
 Vomiting
 Constipation
 Foul smelling stools
 Anemia
 Fatigue
 Osteoporosis
 headache
 Mouth ulcers
 Infertility or miscarriage
 Tigling numbness in hands and feet
 DERMATITIS HERPETIFORMIS
 Depression, irritability, poor memory, trouble concentrating
 Piter, grooved, discolored teeth (children)


Celiac disease reaction with GLUTEN (rye, barley, wheat)
DERMATITIS HERPETIFORMIS:
 itchy blistering rash around elbows, knees, scalp and buttocks.
 Teenege years more in Males
 Clears with gluten free

Wheat Allergy: skin rash, wheexing,abdominal pain, diarrhea

SCREENING:
1. Immediate family member
2. Exposure to gluten <3m
3. Major life event eg:surgery, pregnancy in people genetically predisposed
4. Type 1 Diabetes, thyroid disease other autoimmune diseases
5. Genetic disorders Down syndrome, turner syndrome


The average of person with symptoms to be diagnosed is 4 YEARS

SEROLOGIC TESTING:
1. IgA anti tissue transgluminase tTG
2. IgA endomysial antibody
3. IgG or IgA deamidated gliadin peptides
4. IgA 5% defic

,GENETIC TEST:
 DQ2
 DQ8 gene
 High negative predictive value
 More common in DQ2

DIAGNOSIS:
 Biopsy of small intestine to confirm blood test
 Endoscopically
 Damage of the small villi

60% children and 40% adults will have no symptoms.
->damaged intestinal lining-> MALABSORPTION, OSTEOPOROSIS, INFERTILITE AND
NEUROLOGIC SYMPTOMS

If DIABETES 1 > risk for celiac
Untreated will cause lower blood glucose
Can occur alongside with other autoimmune diseases

If osteoporosis-> Vit D+ Calcium
Supplaments: Fe, Ca, vit D,zinc,folic acid
If resistant to gluten free diet-> STEROIDS (oral or IV)

,INTESTINAL OBSTRUCTION

Small intenstine most commontly affected ILEUS
Large bowel only 15% in SIGMOID COLON

Location of obstruction
Presence of ischemia ->discriminate for treatmnet
Degree of obstruction


1)MECHANICAL OBSTUCTION
 Jejunum or ileum obstruction 4x more than large colon
 EXTRINCIC: surgery,hernia,wound,masses,70% adhesion
 INTRINSIC:hematoma,tumor,intussusception,stricute,stenosis
 INTRALUMINAR:foreign body, fecal or bareim impaction,stones,meconium in infant
 POSTOPERATIVE PTS: 90% due to adhesions, nonsurgical due to hernia

2)PARALYTIC ILEUS:
 Diminished motor activity
 Toxin or trauma
 No physical obstruction or interruption of blood supply
 Disappears after 2-3 d
 Spinal cord injury, GIT surgery, peritonitis,pneumonia,would dehiscence


2)STANGULATION OBSTRUCTION:
 Commpromised blood supply leading to gangrene
 Caused by prolonged mechanical obstruction
 RISK FACTOR: Abdominal surgery which causes adhesions, CD, cancer of abdomen


SYMPTOMS:
 Abdominal distention
 Abdominal fullness
 Gas
 Pain and cramping
 Breth odor
 Constipation
 Diarrhea
 Vomiting
 Fever, peritoneal irritation
 Increased WBC
 Toxicity and shock in ALL typer



DIAGNOSIS:

, 1. Physical exam
2. Fecal aspiration with NGtube
3. XRAY: presence of gas or fluid, BIRD BEAK LESION in colonic volvulus, Foreign
material
4. Barium enema in ILEUS

LABORATORY TESTS:
 Decresead Na,K,CL
 Increase WBC
 Increased SERUM AMYLASE-> irritation of the pancreas

SIGMOIDOSCOPY OR COLONOSCOPY -> to identify the source of obstruction

TREATMENT:
1. Correction of fluid , Ringers solution
2. NG tube to decompress
3. TPN to correct protein def
4. Anaglestic and sedatives
5. Antibiotics to prevent peritonitis
6. AMBULATION IN PARALYTIC ILEUS

SURGERY:
 Closed bowel procedure:lysis of adhesions,intussusetion of hernias
 Enterotomy for foreign bodies
 Resection of bowel for obstructing regions
 Intestinal bypass around obstruction
 Temporary ostomy

MAINTAIN electrolyte and fluid balance->measure intake and output+vital signs
MAINTATIN normal bowel elimination-> stool samples, fluid, record stool,NG tube
MAINTAIN VENTILATION:FOWLERS POSITION->40-60 degrees to relieve abdominal dist
MONITORA abgs

Avoid ENEMAS -> may distort xray image

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