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Endocrine System: Mechanism of Hormone Action: Direct Gene Activation Worksheet Exercise
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Worksheet Exercise on Endocrine System. For review and notes purposes.
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Endocrine System: Mechanism of Hormone Action: Direct Gene Activation1. a. Lipid-soluble hormones such as STEROID and THYROID hormones bind to receptors located IN
THE CELL.
b. Once the hormone binds to the receptor, the CHAPERONE dissociates from the receptor complex.
c. The hormone-receptor complexes act as TRANSCRIPTION FACTOR.
d. The receptor–hormone complex then binds to DNA.
e. The mRNA produces ENZYMES that catalyze biochemical reactions in the cell.
2. Cortisol is classified as a/an STEROID hormone. Name four major actions of cortisol.
1. INHIBITS INFLAMMATION 3. ENHANCES VASOCONSTRICTION
2. PROTEIN BREAKDOWN 4. IMMUNE RESPONSE
These actions are important for the stress response.
3. The main function of thyroid hormones is: REGULATING METABOLIC RATE.
Three other specific functions include:
1. ALTER CARB, LIPID, & PROTEIN METABOLISM
2. ESSENTIAL FOR GROWTH
3. ESSENTIAL FOR NERVOUS SYSTEM DEVELOPMENT & FUNCTION
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