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Study notes Hematology: Classification of Anemia

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  • August 22, 2022
  • 4
  • 2022/2023
  • Class notes
  • Prof. madel quirit
  • All classes
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✓ Is easy to come up with a diagnosis if the anemia is classified together because there are anemias that
have similar manifestation.


 Impaired red cell production
→ In the bone marrow or erythropoietin
 Increased red cell destruction or loss in excess of the ability of the bone marrow to replace such losses
✓ Primarily affects RBCs.


 (only occurs when there is) Higher plasma volume.
✓ the values of the RBC parameters decrease, only because of the higher plasma volume. So, there is a
relative decrease




✓ Anemia may also be categorized through its pathophysiologic means.
✓ It may be due to decreased production of RBCs or due to increased RBC destruction.



✓ Laboratory result
 Reticulocyte count (kinetic approach)
 Mean cell volume (morphologic approach)

Which is BETTER?
**First diagram next page* ***Second diagram next page*
Favors morphologic approach:
 MCV automatically includes as part of the CBC, while retic count (ordered separately) is not.
 There is more equal distribution of patients into separate categories.
→ Because if the morphologic approach is used, it is statistically assumed that 1/3 of the patient
has microcytic anemia, 1/3 of the patient has macrocytic anemia and 1/3 of the patient has
normocytic anemia.

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