3. COMPOSICIÓ
La seqüència d’aminoàcids especifica l’estructura 3D
- Els aminoàcids estan units en combinacions específiques per a una proteïna
determinada.
◼ Una mutació genètica que porti a una substitució per a un aminoàcid incorrecte,
en una proteïna de milers d’aminoàcids, pot provocar que aquesta proteïna tingui
una forma diferent i poc o gens activitat biològica.
- Llargues cadenes d’aminoàcids es pleguen seguint una pauta que depèn de l’ordre
exacte dels aminoàcids.
Es van sintetitzant les proteïnes i es van plegant, això fa que es creï l’estructura de les
proteïnes. L’exemple del vídeo, mostra una proteïna globular, ja que quan es plega
forma una mena de rodona.
4. FORCES QUE AFECTEN A L’ESTRUCTURA:
Increment de G es < 0 per tant
termodinàmicament es un procés favorable,
passa d’estar desordenat a ordenat .
AIXÒ SOLS PER PROTEINES GLOBULARS.
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