Summary
Summary Gringard reactions
- Course
- Institution
Summary of 5 pages for the course Unit 18 - Organic Chemistry III at PEARSON (Gringard reactions)
[Show more]
Seller
Follow
elliebailey
Content preview
Name: Date:A-level Chemistry - Topic 18C: Organic Synthesis
met% Grignard Reagents
have
inside
them
of
Notes halogen ◦ alkane
(
usually
Br / I )
Grignard are
used to make
c- C bonds Mg
reagent
:
•
nucleophilic at
conditions :
dry ether ( solvent )
the carbon reflux
•
unstable
→ made
just before using it Hgv polar covalent bond
though ,
MgBr'e✓en
metal
H -
C
-
I -
☒
it ~
~
Grignard to =c=O
05
methanol reflux reagent
'
reflux
µ
+ At
+
µ
-
'
% '
R
*
8- C in grignard '
H
it ,H °
'
① R' R
'
+
1- 8
'
-
[ in methanol "
f g
OH H -
- -
c.
bond .
µ ,
-
É I -
-
H + Ht H H
'
OH
'
'
"
② add dilute H H R reflux
acid ( reduce
c=o )
.
_
.
-
-
"
if it if H
µ
OH
H -
c- Cdc -
H I c- I R
!
H
-
-
-
it it it Hit r
' '
ñe and
'
all
dry for
•
, Questions
1. Suggest a two-step synthesis of from using a
Grignard reagent in one of the steps.
Br
' I
→ M9B ' reflux
Mg
◦
+
◦
dry ether .
H
¥
fl
☒
◦ "
Mg Br reflex
c- d- c"
- •
2) ta -
→
•
Ht
if I
'
H
,
2. Suggest a two-step synthesis of from using a
Grignard reagent in one of the steps.
it Brt Mg → ' M9 " •
reflex
•
dry ether .
AMgBr+ ( 0, →
ÉOH
reflex
•
•
At
3. Show how pentan-3-ol can be synthesised from propanal and bromoethane using
ÉÉ
Grignard chemistry.
it it
It c- c- Br Mg
→←
Mg Br
-
+
-
ti't It if
" "
it it , it 9 ◦
the
•
H -
c- c- MgBr +
→ A- c- c- c- It
Hit
,
, •
µ
it f * ; µ
,
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller elliebailey. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $4.54. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
77254 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now