Biomedische Wetenschappen, Moleculaire Levenswetenschappen, Metabolisme En
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The Mitochondria
Contents
Structure of the mitochondria and their function......................................................................3
Mitochondria Associated Memebranes (MAMs)........................................................................4
Calcium; Ca2+..............................................................................................................................5
Mitochondrial DNA; mtDNA........................................................................................................6
Characteristics of the mtDNA.................................................................................................6
Mitochondria DNA mutations and diseases...........................................................................8
A list of the clinical guidelines that have been generated from our experience of
investigating and managing patients with mtDNA mutations............................................8
, Mitochondria are membrane-
bound cell organelles
(mitochondrion, singular)
that generate most of the
chemical energy needed to
power the cell's biochemical
reactions. Chemical energy
produced by the mitochondria is
stored in a small molecule called
adenosine triphosphate (ATP). In
addition to producing energy, mitochondria store calcium for cell signaling activities,
generate heat, and mediate cell growth and death.
Mitochondria contain their own small chromosomes. Generally, mitochondria, and therefore
mitochondrial DNA, are inherited only from the mother.
Mitochondria are membrane-bound organelles, but they're membrane-bound with two
different membranes. And that's quite unusual for an intercellular organelle. Those
membranes function in the purpose of mitochondria, which is essentially to produce energy.
Different cells have different amounts of mitochondria. Red blood cells don’t contain any
mitochondria.
https://www.britannica.com/biography/Albert-Claude
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