Summary
Samenvatting pathologie - schildklier
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Wat: Te hard werkende schildklierOorzaak: Verschillende mogelijke oorzaken
- Ziekte van Graves
- Multinodulaire goiter
- Autonome nodule
- Oversubstitutie met schildklierhormoon
Symptomen: HYPERTHYROÏDIE
- Gewichtsverlies
- Versnelde hartslag, hartkloppingen
- Gejaagd gevoel
- Zweten
- Tremor (beven)
- Emotioneel
- Slaapstoornissen
Behandeling:
- Afhankelijk van de oorzaak
Wat: Auto-immuunziekte
Oorzaak:
- Antilichamen tegen lichaamseigen
schildklierweefsel, binden op de TSH-
receptor op het schildklierweefsel
Stimuleren schildklier tot productie
schildklierhormoon
Toename in T4/T3 (thyroxine)
Hyperthyroïdie
Symptomen:
- Goiter
- Hyperthyroïdie
- Oogsymptomen: exoftalmie (ogen naar
voren opengespreid), oogspierverlamming,
uitdroging ZIEKTE VAN GRAVES
Klinisch onderzoek:
- Kliniek
- Bloedname met bepalen T4 (hoog), TSH
(laag) en anti-lichamen (TSI-antistoffen)
Behandeling:
- Anti-thyroïdea = schildklier-inhiberende
medicatie
- Radio-iodium
Radio-actieve stof gebonden aan
iodium
Inwendige bestraling van de
schildklier
- Heelkunde: totale thyroïdectomie
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