100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
MGZ Q2 Nature $5.89   Add to cart

Class notes

MGZ Q2 Nature

 8 views  0 purchase
  • Course
  • Institution

Alle gemaakt aantekeningen door het kwartaal heen van MGZ Q2 nature. Inclusief uitwerkingen van de e-learningen en een aantal ZSO's.

Preview 4 out of 77  pages

  • September 21, 2022
  • 77
  • 2020/2021
  • Class notes
  • -
  • All classes
avatar-seller
MGZ Q2 Nature
Inhoud
De gezonde cel ........................................................................................................................................ 3
HC ........................................................................................................................................................ 3
E-learning............................................................................................................................................. 4
Endoplasmatisch reticulum (RE)...................................................................................................... 6
Lysosoom ......................................................................................................................................... 7
Mitochondrium................................................................................................................................ 7
Vragenuur ............................................................................................................................................ 8
RC......................................................................................................................................................... 8
Genetica ................................................................................................................................................ 10
Variatie .............................................................................................................................................. 10
Populatie ........................................................................................................................................... 13
RC afsluitend...................................................................................................................................... 15
Cellulaire besluitvorming....................................................................................................................... 16
Communicatie ................................................................................................................................... 16
E-learning........................................................................................................................................... 19
Celdeling en andere celbesluiten .......................................................................................................... 21
Proliferation................................................................................................................................... 21
Apoptosis ....................................................................................................................................... 24
Stamcellen ..................................................................................................................................... 24
E-learning........................................................................................................................................... 24
Celdeling ........................................................................................................................................ 24
DNA-replicatie ............................................................................................................................... 25
Vragenuur .......................................................................................................................................... 26
Besluiten ............................................................................................................................................ 28
RC....................................................................................................................................................... 30
Genexpressie ......................................................................................................................................... 30
HC ...................................................................................................................................................... 30
HC ...................................................................................................................................................... 34
e-learning .......................................................................................................................................... 39
Vragenuur .......................................................................................................................................... 41
ZSO-genexpressie .................................................................................................................................. 42
Opbouw DNA ..................................................................................................................................... 42


1

, Transcriptie e RNA-processing .......................................................................................................... 43
Eitwitroute......................................................................................................................................... 44
Van cel naar weefsel.............................................................................................................................. 47
Stamcellen ......................................................................................................................................... 47
ZSO..................................................................................................................................................... 47
Werkgroep ......................................................................................................................................... 48
Epitheel, klieren en bindweefsel ....................................................................................................... 48
HC ...................................................................................................................................................... 48
Epitheel.......................................................................................................................................... 48
Bindweefsel ................................................................................................................................... 51
ZSO epitheel ...................................................................................................................................... 53
ZSO-bindweefsel................................................................................................................................ 54
Practicum........................................................................................................................................... 55
Kraakbeen en botweefsel .................................................................................................................. 56
Hoorcollege ....................................................................................................................................... 56
Kraakbeen:..................................................................................................................................... 56
Botweefsel ..................................................................................................................................... 58
Practicum........................................................................................................................................... 60
Extracellulaire matrix ........................................................................................................................ 63
Hoorcollege ................................................................................................................................... 63
Collageen ....................................................................................................................................... 63
Elastische vezels ............................................................................................................................ 64
Ground substance ......................................................................................................................... 64
ZSO................................................................................................................................................. 65
Pathologie.......................................................................................................................................... 65
Afsluitend RC ..................................................................................................................................... 65
Embryologie........................................................................................................................................... 66
Hoorcollege ....................................................................................................................................... 66
Vragenuur .......................................................................................................................................... 68
E-learning embryologie ..................................................................................................................... 69
Werkgroep ......................................................................................................................................... 73
E-learning zenuwstelsel ..................................................................................................................... 75
E-learning spijsverteringstelsel.......................................................................................................... 76




2

,De gezonde cel
HC
70 kilo mens= 1013 eukaryote cellen

Microbioom= 1014 bacteriën + 1 kilo

RNA-molecuul was het begin van de cel en scheiding van milieu (hieruit zijn eukaryoten en
prokaryoten voortgekomen)

DNA > RNA > eiwit

Een gezonde cel bevat: DNA, RNA, eiwitten, lipids, polysachariden, solutes/lons en H2O en verder nog
organellen (= een subcompartiment binnen een eukaryote cel met een functie).

Cytoskelet= de botten en spieren van een cel; intermediare filamenten (overal in de cel) zorgen voor
treksterkte, microtubuli, actine filament (periferie en cortex van de cel).

Intermediare filamenten= niet meteen kapotgaan
en iets kunnen opvangen. Komt voor in cytosol en
lamine in de kern. Beide uiteinden zijn hetzelfde,
dit zorgt voor stabiliteit.

Microtubuli= door verschillende kanten heeft een
kant gehydroliseerd waardoor die kant minder
affiniteit heeft. – uiteinde wordt vastgezet (in
centrosoom) zodat het niet telkens afbreekt en
kan binden aan de + uiteinde (deze kunnen
groeien). Spoelfiguur. Het microtubuli speelt een
rol waar alles ligt in de cel en het transport. AGP.
Bevind zich meer in het midden.

Actine filamenten= dun en flexibel, vooral in de cortex, periferie (buitenkant). Cel migratie.
Polymeren van actine. – en + kant. Deze binden ATP, hierbij binden ze graag aan elkaar. Bij ADP
vallen ze uit elkaar. Treadmilling.



Vorm is functie, daarom is cytoskelet heel belangrijk. Het membraan is asymmetrisch verdeelt met
(fosfo)lipiden.

Glycolipiden= zit op het lipide nog een bos suiker erboven op




3

, De pijl geeft aan hoe makkelijk het erdoor heen kan.

Er zijn eiwitten nodig om ze er dan doorheen te
krijgen.




Lading is ook nog belangrijk (electro) chemische
gradiënt. De binnenkant is ligt -, dus + gaat
makkelijker naar binnen.

Receptoren, voor die er niet doorheen kunnen of
naar binnen getransporteerd kunnen worden.

Kern, mitochondrion, endoplasmatische reticulum (synthese, opslag, verdeling), golgi-apparaat
(transport, verdeling, secretie), peroxisoom (vetzuren afbraken, galzuren maken en H2O2), lysosoom
(komen via het golgi, ze doen ook aan recycling)

Heterofagie= iets vreemd opeten

Autofagie= iets wat in het lichaam niet meer goed functioneert wordt opgeruimd.



E-learning
Hematoxyline kleurt zure groepen blauw en eosine kleurt basische componenten rood, HE-kleuring.

Je kunt ook specifieke structuren zichtbaar maken door gekleurde eiwitten,
fluorescentiemicroscopie.

Confocale-laser-scanning-microscopie (CLSM)= serie digitale beelden die samen een drie-
dimensionaal beeld geeft.

Nucleus= kern

Goud of een zwaar metaal wordt gebruikt bij Immuno-elektronmicroscopie (IEM) want dit laat slecht
elektronen door en wordt daardoor donker.




4

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller ellendeboer. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $5.89. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67474 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$5.89
  • (0)
  Add to cart